| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_026203m |
| Family | GH47 |
| Protein Properties | Length: 463 Molecular Weight: 52292.1 Isoelectric Point: 6.4313 |
| Chromosome | Chromosome/Scaffold: 04177 Start: 306667 End: 321943 |
| Description | alpha-mannosidase 2 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH47 | 33 | 417 | 0 |
| AMLHAWSSYEKYAWGHDELQPQTKNGVDSFGGLGATLIDALDTLFIMGFDEQFQRAREWVANSLDFNKDYDASVFETTIRVVGGLLSAYDLSSDKVFLEK AKDIADRLLPAWNTSTGIPYNIINLAHGNAHNPGWTGGDSILADSGTEQLEFIALSQRTGDPKYQLKAEKVILELNKTFPDDGLLPIYINPDKGTGSYST ITFGAMGDSFYEYLLKVWIQGNKTSTVRHYREMWEKSMKGLLSLVRKTTPSSFTYICEKSGDMLADKMDELACFAPGMIALGSSGYGPADSQKFLSLAEE LAWTCYNFYQSTPTKLAGENYFFHPGQDMSVGTSWNILRPETIESLFYLWRLTGNKTYQEWGWNIFQAFEKNSRHETGYVGLKDL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 463 Download |
| SIKSITSKSS KYSQKAIHDD PIDIERREKV KEAMLHAWSS YEKYAWGHDE LQPQTKNGVD 60 SFGGLGATLI DALDTLFIMG FDEQFQRARE WVANSLDFNK DYDASVFETT IRVVGGLLSA 120 YDLSSDKVFL EKAKDIADRL LPAWNTSTGI PYNIINLAHG NAHNPGWTGG DSILADSGTE 180 QLEFIALSQR TGDPKYQLKA EKVILELNKT FPDDGLLPIY INPDKGTGSY STITFGAMGD 240 SFYEYLLKVW IQGNKTSTVR HYREMWEKSM KGLLSLVRKT TPSSFTYICE KSGDMLADKM 300 DELACFAPGM IALGSSGYGP ADSQKFLSLA EELAWTCYNF YQSTPTKLAG ENYFFHPGQD 360 MSVGTSWNIL RPETIESLFY LWRLTGNKTY QEWGWNIFQA FEKNSRHETG YVGLKDLLCT 420 CGRKVFIHNS LPKKWFLNEY ACKRITGSSG RGSWYQLPWM RV* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PTZ00470 | PTZ00470 | 1.0e-170 | 17 | 418 | 411 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 5.0e-177 | 33 | 416 | 401 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF16414.1 | 0 | 3 | 417 | 85 | 500 | AF126550_1 mannosyl-oligosaccharide 1,2-alpha-mannosidase [Glycine max] |
| EMBL | CBI18472.1 | 0 | 5 | 417 | 81 | 494 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002310939.1 | 0 | 14 | 417 | 87 | 490 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325257.1 | 0 | 21 | 417 | 95 | 491 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528166.1 | 0 | 4 | 417 | 33 | 447 | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 25 | 417 | 19 | 416 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 21 | 410 | 4 | 397 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 21 | 410 | 4 | 397 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 21 | 410 | 4 | 397 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 21 | 410 | 82 | 475 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO780776 | 414 | 17 | 417 | 0 |
| DY974119 | 307 | 94 | 400 | 0 |
| GO877285 | 308 | 81 | 388 | 0 |
| GO877285 | 19 | 386 | 404 | 0.053 |
| GO877285 | 15 | 403 | 417 | 0.053 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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