| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_028198m |
| Family | GT47 |
| Protein Properties | Length: 559 Molecular Weight: 63474.6 Isoelectric Point: 9.216 |
| Chromosome | Chromosome/Scaffold: 06550 Start: 89015 End: 92022 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 221 | 502 | 0 |
| EKQFKVFVYEEGEPPVFHNGPCKSIYSMEGNFIHRMEMDDHFRTKDPNKAHVYFLPFSVVMMVRFVYVRNSHDFGPIKRTVRDYVGLIAGKYPFWNRSLG ADHFMLACHDWGPETSFSVPHLAKNSIRALCNANTSERFNPMKDVSFPEINLQTGTTKGLIGGPSPSRRSILAFFAGGLHGPIRPIILEHWENKDDDMSV HRYLPKGVSYYEMMRKSKFCLCPSGYEVASPRVVEAFYTGCVPVLISDHYVPPFSDVLNWKAFSVEVPVSDIPNLKRILMSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 559 Download |
| MGHAWRSSSS SSSSPIKLLL FMAPLVLVSG FVAILGPKFS SLEFLSSHSW LLGFGAADSL 60 NISVPASSHA KENNESRLLD LHPRVAMVGM EVEDHSAEEK KALSDQYSAF NRSSASPPPS 120 SPPPPPVRYF PAVDIQEPNA SEEGKQISRN KTSIVSLDLS IKNKHEKEHS SLERLEAALQ 180 IARSAIKEAK FGDQWQDPEY VPMGPMYWNS KVFHRSYLEM EKQFKVFVYE EGEPPVFHNG 240 PCKSIYSMEG NFIHRMEMDD HFRTKDPNKA HVYFLPFSVV MMVRFVYVRN SHDFGPIKRT 300 VRDYVGLIAG KYPFWNRSLG ADHFMLACHD WGPETSFSVP HLAKNSIRAL CNANTSERFN 360 PMKDVSFPEI NLQTGTTKGL IGGPSPSRRS ILAFFAGGLH GPIRPIILEH WENKDDDMSV 420 HRYLPKGVSY YEMMRKSKFC LCPSGYEVAS PRVVEAFYTG CVPVLISDHY VPPFSDVLNW 480 KAFSVEVPVS DIPNLKRILM SISTRQYIRM QRRGQQIRRH FEVNSPPKRY DVYHMILHSI 540 WLRRLNARIY DSPRAITS* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-65 | 220 | 502 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08605.1 | 0 | 155 | 549 | 11 | 405 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_001031828.1 | 0 | 155 | 549 | 121 | 515 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002284018.1 | 0 | 220 | 550 | 1 | 331 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002326234.1 | 0 | 220 | 547 | 1 | 328 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528630.1 | 0 | 3 | 558 | 18 | 574 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
