| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_028283m |
| Family | AA7 |
| Protein Properties | Length: 262 Molecular Weight: 29024.4 Isoelectric Point: 8.0343 |
| Chromosome | Chromosome/Scaffold: 07478 Start: 778016 End: 778836 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| AA7 | 73 | 230 | 0 |
| RNARWNTSTTPKPLIIITPKQIPHVQAAVVCTKKVGYQLKVRSGGHDYEGISYVSDVPFFLLDMFNLRSINVDVKTESAWVQTGATLGEVYYRIWEKSKV HGFPAGFCPTVGVGGHISGGGYGNMLKKYVLASDNVLDAQIVDANGKLLDRKAMGEDL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 262 Download |
| MAKITPLSTF LVLLLFNLSS SFPSFSLAAP APDVSVYESF LQCLDYNTNP QDQISDLVYS 60 QAYNTSFLRA YIRNARWNTS TTPKPLIIIT PKQIPHVQAA VVCTKKVGYQ LKVRSGGHDY 120 EGISYVSDVP FFLLDMFNLR SINVDVKTES AWVQTGATLG EVYYRIWEKS KVHGFPAGFC 180 PTVGVGGHIS GGGYGNMLKK YVLASDNVLD AQIVDANGKL LDRKAMGEDL VLTLDQNATT 240 DVVYKWQLVA PKTDNAIFMR ML |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 5.0e-5 | 68 | 222 | 162 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 1.0e-17 | 85 | 222 | 139 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002276003.1 | 0 | 35 | 262 | 29 | 291 | PREDICTED: hypothetical protein, partial [Vitis vinifera] |
| RefSeq | XP_002299028.1 | 0 | 1 | 262 | 1 | 293 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002317087.1 | 0 | 1 | 262 | 1 | 293 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523157.1 | 0 | 1 | 262 | 1 | 297 | Reticuline oxidase precursor, putative [Ricinus communis] |
| RefSeq | XP_002523158.1 | 0 | 33 | 262 | 33 | 297 | Reticuline oxidase precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 38 | 258 | 5 | 231 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsj_B | 0 | 32 | 262 | 3 | 265 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsj_A | 0 | 32 | 262 | 3 | 265 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsh_A | 0 | 32 | 262 | 3 | 265 | A Chain A, Crystal Structure Of Phl P 4, A Grass Pollen Allergen With Glucose Dehydrogenase Activity |
| PDB | 4dns_B | 0 | 29 | 262 | 1 | 267 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
