| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_029120m |
| Family | GT47 |
| Protein Properties | Length: 419 Molecular Weight: 47363 Isoelectric Point: 8.8197 |
| Chromosome | Chromosome/Scaffold: 02831 Start: 365235 End: 366491 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 30 | 346 | 0 |
| SLYVYQLPPEFNVGLLRNCSHLNIYTNMCPHVSNNGLGQPISTTGTWFATHQFLAEMIFHARIENHPCRTWDPNLANLFYVPFYGGLHSSSKFREANHTA RDELAVRLVEYIKIQPWWQRHHGYDHFLALGRTAWDFMRITNGGPDFGANCLLNLPPVKNMSVLTVERHPWQGVNQYGVPYPSYFHPSNVVQMRTWQQKM IRSERKHLFSFVGGPRKGVEKAAVRDELIRQCKESTRCFLVKCGGGGGKCHEPFKVLKVLSRSQFCLQAPGDSFTRRSTFDSVLAGCIPVFFSPHTAYTQ YSWYFPANGSDYSVYID | |||
| Full Sequence |
|---|
| Protein Sequence Length: 419 Download |
| FFFSSTNTHL PFPNATTKEL SPITCPGNLS LYVYQLPPEF NVGLLRNCSH LNIYTNMCPH 60 VSNNGLGQPI STTGTWFATH QFLAEMIFHA RIENHPCRTW DPNLANLFYV PFYGGLHSSS 120 KFREANHTAR DELAVRLVEY IKIQPWWQRH HGYDHFLALG RTAWDFMRIT NGGPDFGANC 180 LLNLPPVKNM SVLTVERHPW QGVNQYGVPY PSYFHPSNVV QMRTWQQKMI RSERKHLFSF 240 VGGPRKGVEK AAVRDELIRQ CKESTRCFLV KCGGGGGKCH EPFKVLKVLS RSQFCLQAPG 300 DSFTRRSTFD SVLAGCIPVF FSPHTAYTQY SWYFPANGSD YSVYIDLDGE KGNVKKSIEE 360 ELSKISSDRV EKMRRKIMEI MPSITYAHPN SSDVGFGDAV DVALEALLKN AGSKLGFL* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-60 | 29 | 346 | 329 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC42883.1 | 0 | 1 | 411 | 46 | 447 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_177014.1 | 0 | 1 | 411 | 46 | 447 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270383.1 | 0 | 27 | 415 | 121 | 503 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300452.1 | 0 | 25 | 407 | 1 | 391 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002336132.1 | 0 | 16 | 407 | 12 | 412 | predicted protein [Populus trichocarpa] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DY265125 | 319 | 32 | 342 | 0 |
| FC899396 | 312 | 32 | 335 | 0 |
| DY298787 | 303 | 59 | 353 | 0 |
| FC884199 | 296 | 59 | 346 | 0 |
| DY277080 | 305 | 29 | 324 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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