| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_030165m |
| Family | GT47 |
| Protein Properties | Length: 486 Molecular Weight: 56156.6 Isoelectric Point: 9.5535 |
| Chromosome | Chromosome/Scaffold: 00847 Start: 1542567 End: 1545906 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 153 | 437 | 0 |
| ERRFKVYVYSEGDLPIVHDGPCKDIYTIEGRFIQEMEHGARRFRTTDPRRAHVYFMPFSVTWMVKYLYKPLTYDLTPLRQFVSDYVRVVSTKYPFWNRTC GADHFMLACHDWGPHASRANPFLYNTSIRVLCNANTSEGFNPRKDVSLPEIHLYNGNFPPQLLSPPPANTSRPYLAFFAGGLHGPIRPLLVNQWKDRDSD LRVFEYLPKDLDYYSFMLQSKFCLCPSGHEVASPRIVEAIYAECVPVILSNYYVLPFSDVLRWDAFSVQVNVSEIPRLKEVLSSV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 486 Download |
| MDMKLYGYSF LHCFLILLFI FFILILSGFF NSTSFSIFSR SNFQSSISVP AVQLQTLVSH 60 SDQIHDVHSA NSSYTSPVNQ FRNSTAIRKI SKLISREEEL LEQGLARARA SIRKAGTSSV 120 IVSSIAGVNR SDVDRVVVYR NRAAFYRSYL EMERRFKVYV YSEGDLPIVH DGPCKDIYTI 180 EGRFIQEMEH GARRFRTTDP RRAHVYFMPF SVTWMVKYLY KPLTYDLTPL RQFVSDYVRV 240 VSTKYPFWNR TCGADHFMLA CHDWGPHASR ANPFLYNTSI RVLCNANTSE GFNPRKDVSL 300 PEIHLYNGNF PPQLLSPPPA NTSRPYLAFF AGGLHGPIRP LLVNQWKDRD SDLRVFEYLP 360 KDLDYYSFML QSKFCLCPSG HEVASPRIVE AIYAECVPVI LSNYYVLPFS DVLRWDAFSV 420 QVNVSEIPRL KEVLSSVPED KYKNLKEGLR AVRRHFVLNQ PAKRFDVFYM ILHSIWLRRI 480 NLRLA* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-63 | 152 | 437 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI21064.1 | 0 | 41 | 485 | 37 | 478 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197913.4 | 0 | 83 | 485 | 85 | 480 | catalytic [Arabidopsis thaliana] |
| RefSeq | XP_002285237.1 | 0 | 152 | 485 | 1 | 334 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002324871.1 | 0 | 152 | 485 | 1 | 334 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002515489.1 | 0 | 1 | 485 | 1 | 481 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
