| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_030588m |
| Family | CE10 |
| Protein Properties | Length: 305 Molecular Weight: 33313.7 Isoelectric Point: 5.3523 |
| Chromosome | Chromosome/Scaffold: 04393 Start: 134707 End: 135621 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 41 | 301 | 0 |
| DGISTKDVLIVPETGVSARIFIPSNINSGQKIPLLVYFHGGGFLIGSPFCPTYHNFLASLVTAANVIAVSIDYRLAPENPLPTAYEDSWVALKWVASHCN GGGSEPWLKDHADFGRVFLAGDSAGANIVHNVGVQASVEDLNGVKLFGICLIHPYFGRKEGGVDDSWLFVSPDTSGFNDLRINPALDSRLASLGCTRVLI CIAEKDKLRERGVFYYETLVKSGWNGEVEIVETEGEEHVFHLFKPNCEHAVALLKKLASFM | |||
| Full Sequence |
|---|
| Protein Sequence Length: 305 Download |
| MNSTSTEISF EFGSFFRAYK DGRVERFFGT DKVPASINSP DGISTKDVLI VPETGVSARI 60 FIPSNINSGQ KIPLLVYFHG GGFLIGSPFC PTYHNFLASL VTAANVIAVS IDYRLAPENP 120 LPTAYEDSWV ALKWVASHCN GGGSEPWLKD HADFGRVFLA GDSAGANIVH NVGVQASVED 180 LNGVKLFGIC LIHPYFGRKE GGVDDSWLFV SPDTSGFNDL RINPALDSRL ASLGCTRVLI 240 CIAEKDKLRE RGVFYYETLV KSGWNGEVEI VETEGEEHVF HLFKPNCEHA VALLKKLASF 300 MNQD* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG2272 | PnbA | 1.0e-10 | 67 | 169 | 116 | + Carboxylesterase type B [Lipid metabolism] | ||
| pfam00135 | COesterase | 5.0e-13 | 60 | 170 | 124 | + Carboxylesterase family. | ||
| cd00312 | Esterase_lipase | 7.0e-14 | 60 | 170 | 120 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| COG0657 | Aes | 5.0e-33 | 34 | 302 | 288 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 3.0e-52 | 75 | 282 | 223 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002285071.1 | 0 | 1 | 304 | 1 | 320 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002285075.1 | 0 | 1 | 304 | 1 | 323 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002285076.1 | 0 | 1 | 304 | 1 | 323 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313844.1 | 0 | 1 | 303 | 1 | 303 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002518789.1 | 0 | 1 | 303 | 2 | 304 | catalytic, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2zsi_A | 5e-32 | 32 | 304 | 59 | 351 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 2zsh_A | 5e-32 | 32 | 304 | 59 | 351 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 2o7v_A | 9e-32 | 32 | 263 | 37 | 293 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 2o7r_A | 9e-32 | 32 | 263 | 37 | 293 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_F | 2e-29 | 21 | 304 | 37 | 350 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| GO920318 | 259 | 1 | 258 | 0 |
| DN503474 | 244 | 1 | 243 | 0 |
| FY915135 | 255 | 4 | 257 | 0 |
| DY294195 | 313 | 5 | 304 | 0 |
| FC907836 | 313 | 5 | 304 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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