| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_031633m |
| Family | GT47 |
| Protein Properties | Length: 328 Molecular Weight: 37724.4 Isoelectric Point: 9.7223 |
| Chromosome | Chromosome/Scaffold: 03614 Start: 1826033 End: 1827227 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 3 | 279 | 0 |
| RSFKIYAYPHRQNDPFANALLPVDFEPRGNYASESYFKKVLMKSHFITKDPTKADLFFLPFSIARLRHDPRIGVGGIQDFIRDYISNISRKYPYWNRTGG ADHFYVACHSIGRSAMEKAEEVKFNAIQVVCSSSYFLSGHIAHKDASLPQVWPRQGDPPGIASSKRKKLAFFAGSINSPVRERLLQVWRNDTEIFVHFGR LTTPYADELLGSKFCFHVKGFEVNTARIADSLYYGCVPVIIANHYDLPFTDILNWKSFSVVVATLDIPLLKKILHGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 328 Download |
| MNRSFKIYAY PHRQNDPFAN ALLPVDFEPR GNYASESYFK KVLMKSHFIT KDPTKADLFF 60 LPFSIARLRH DPRIGVGGIQ DFIRDYISNI SRKYPYWNRT GGADHFYVAC HSIGRSAMEK 120 AEEVKFNAIQ VVCSSSYFLS GHIAHKDASL PQVWPRQGDP PGIASSKRKK LAFFAGSINS 180 PVRERLLQVW RNDTEIFVHF GRLTTPYADE LLGSKFCFHV KGFEVNTARI ADSLYYGCVP 240 VIIANHYDLP FTDILNWKSF SVVVATLDIP LLKKILHGIS SEKYQMLQKN VLEVRNHFQW 300 NLPPVDYDAF NMVMYELWLR RSSVRIP* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-67 | 1 | 279 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABD28410.1 | 0 | 1 | 326 | 155 | 481 | Exostosin-like [Medicago truncatula] |
| EMBL | CBI39073.1 | 0 | 1 | 327 | 120 | 446 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265438.1 | 0 | 1 | 327 | 118 | 444 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325425.1 | 0 | 1 | 326 | 1 | 322 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002525728.1 | 0 | 1 | 326 | 1 | 326 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| ES827236 | 284 | 43 | 326 | 0 |
| DT765011 | 253 | 73 | 325 | 0 |
| JK517670 | 270 | 1 | 270 | 0 |
| DY943505 | 267 | 33 | 298 | 0 |
| CJ769259 | 255 | 69 | 322 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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