| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_032775m |
| Family | GT47 |
| Protein Properties | Length: 449 Molecular Weight: 52139.7 Isoelectric Point: 9.5162 |
| Chromosome | Chromosome/Scaffold: 06916 Start: 391939 End: 393285 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 19 | 360 | 0 |
| CSGRYIYVHDLPSQFNDDLIKHCESLSEWTNMCFFMSNLGLGPRLGNSEKVFSNTGWYDTNQFMLEVIFHNRMKQYKCLTNDSSLASAIFVPYYAGLDVV RYLWNSHRSVRDFCSLNLVKWLRETPEWKRLWGRDHFLVAGRITWDFRRITKSADWGNRLMLLPESKNMTMLTIEASPWSQNDFAIPYPTYFHPSRDGEV FQWQHKMRRTKRRFLFSFAGGARPNLTNSIRGEIINQCLATRRRCKLLDCVSRSNGCYKPVYVMKIFQMSTFCLQPSGDSYTRRSTFDSILAGCIPVFFH PGSAYVQYLWHFPKDYTKYSVFIPANKVKKGKVSIERTLSRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 449 Download |
| EEKIEEVSDP SSDSDSGPCS GRYIYVHDLP SQFNDDLIKH CESLSEWTNM CFFMSNLGLG 60 PRLGNSEKVF SNTGWYDTNQ FMLEVIFHNR MKQYKCLTND SSLASAIFVP YYAGLDVVRY 120 LWNSHRSVRD FCSLNLVKWL RETPEWKRLW GRDHFLVAGR ITWDFRRITK SADWGNRLML 180 LPESKNMTML TIEASPWSQN DFAIPYPTYF HPSRDGEVFQ WQHKMRRTKR RFLFSFAGGA 240 RPNLTNSIRG EIINQCLATR RRCKLLDCVS RSNGCYKPVY VMKIFQMSTF CLQPSGDSYT 300 RRSTFDSILA GCIPVFFHPG SAYVQYLWHF PKDYTKYSVF IPANKVKKGK VSIERTLSRI 360 PKAKVLAMRD QVIKLIPGVV YANPRSSLET LEDAFDITID GVLEKVKKTR RDIKQGKDVS 420 DNGEEFTWKK RLFGTVGKHE WDPFFDRS* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-66 | 22 | 360 | 355 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN64889.1 | 0 | 15 | 431 | 296 | 713 | hypothetical protein [Vitis vinifera] |
| GenBank | EEC74507.1 | 0 | 11 | 447 | 136 | 576 | hypothetical protein OsI_09988 [Oryza sativa Indica Group] |
| RefSeq | NP_180468.1 | 0 | 10 | 447 | 280 | 719 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280815.1 | 0 | 15 | 448 | 89 | 524 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313430.1 | 0 | 11 | 448 | 132 | 570 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EL456596 | 271 | 64 | 333 | 0 |
| JG636298 | 265 | 90 | 353 | 0 |
| CX076275 | 262 | 93 | 353 | 0 |
| CF668912 | 282 | 132 | 412 | 0 |
| GR934411 | 265 | 22 | 285 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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