| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_032917m |
| Family | GT47 |
| Protein Properties | Length: 500 Molecular Weight: 57438 Isoelectric Point: 9.8549 |
| Chromosome | Chromosome/Scaffold: 03614 Start: 1554776 End: 1557015 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 108 | 423 | 0 |
| PLKVFMYDLPSQFHFELLDWIPQAGSVWPDLRTKIPAYPGGLNLQHSIEYWLTLDLLASETPGFPRAGSAIRIRNSSEADVIFVPFFSSLSYNRYSKVNP HQKKSKNKLLQQKLVKFVISQREWKRSGGRNHVILAHHPNSLLQARMKLWPAMFILADFGRYPPNIANVEKDVIAPYKHVIRSYVNDLSNFDNRPILLYF QGAIYRKAGGHVRQELFYLLKDEKDVHFQFGSVKNNGINKASKGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPYEDVLDYSQFCIFVRA SDAIKGKFLMNLIRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 500 Download |
| MAEKHVSSFV AVSKKYLLCL FSFILALFIL SWFFLLPSTD RPNFIDHSLL TNAFRSTTDS 60 GSSHSWNQKN VEPLLGSRGG GGDEETAQEK VAVKEVKCNV HNENNTEPLK VFMYDLPSQF 120 HFELLDWIPQ AGSVWPDLRT KIPAYPGGLN LQHSIEYWLT LDLLASETPG FPRAGSAIRI 180 RNSSEADVIF VPFFSSLSYN RYSKVNPHQK KSKNKLLQQK LVKFVISQRE WKRSGGRNHV 240 ILAHHPNSLL QARMKLWPAM FILADFGRYP PNIANVEKDV IAPYKHVIRS YVNDLSNFDN 300 RPILLYFQGA IYRKAGGHVR QELFYLLKDE KDVHFQFGSV KNNGINKASK GMHSSKFCLN 360 IAGDTPSSNR LFDAIASHCV PVIISDDIEL PYEDVLDYSQ FCIFVRASDA IKGKFLMNLI 420 RGIGKDEWTR MWQKLKEVEH FFEFQYPSKE DDAVQMIWQA VARKVPAMRM KIHKSMRFSR 480 SLTRKHRELR EVPTPSNFW* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-52 | 106 | 423 | 328 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33321.1 | 0 | 1 | 499 | 1 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | XP_002268382.1 | 0 | 38 | 499 | 38 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002319201.1 | 0 | 1 | 479 | 3 | 450 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325457.1 | 0 | 77 | 499 | 41 | 463 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530948.1 | 0 | 1 | 495 | 1 | 496 | catalytic, putative [Ricinus communis] |
