| Basic Information | |
|---|---|
| Species | Carica papaya |
| Cazyme ID | evm.TU.contig_32334.1 |
| Family | CE10 |
| Protein Properties | Length: 321 Molecular Weight: 35017.8 Isoelectric Point: 5.1957 |
| Chromosome | Chromosome/Scaffold: 32334 Start: 4866 End: 5828 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 37 | 317 | 0 |
| PEQDPDTGVSSKDVIISLNPPISARLYLPNNLPNKKLPILVYFHGGAFCIESAFSFLDHRYLNNMVSEAQVVGVSVEYRLAPEHPLPTAYQDCWDALQWV ASHSIKDKLHNDPWLADFGDFSGLFIGGDSAGANIAHNVAMRAGNEGLSGGVKIEGTWLAQPFFWASSAIGVEPEKRLPAKVWNVVWPSAPGGVDNPMIN PVGEGCRKELAGLGCSRLLVCVAEKDTFRERGVLYCDAVKESGWEGEVEFFEVKGEDHGFHIFHPYTVNSKAMIKRLASFL | |||
| Full Sequence |
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| Protein Sequence Length: 321 Download |
| MGSVSNEVVI ELTPFIRVYK DGYVERLAGS PIVPPSPEQD PDTGVSSKDV IISLNPPISA 60 RLYLPNNLPN KKLPILVYFH GGAFCIESAF SFLDHRYLNN MVSEAQVVGV SVEYRLAPEH 120 PLPTAYQDCW DALQWVASHS IKDKLHNDPW LADFGDFSGL FIGGDSAGAN IAHNVAMRAG 180 NEGLSGGVKI EGTWLAQPFF WASSAIGVEP EKRLPAKVWN VVWPSAPGGV DNPMINPVGE 240 GCRKELAGLG CSRLLVCVAE KDTFRERGVL YCDAVKESGW EGEVEFFEVK GEDHGFHIFH 300 PYTVNSKAMI KRLASFLSGN * 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00312 | Esterase_lipase | 0.0003 | 75 | 184 | 121 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| COG2272 | PnbA | 0.0002 | 75 | 172 | 113 | + Carboxylesterase type B [Lipid metabolism] | ||
| PRK10162 | PRK10162 | 7.0e-8 | 57 | 187 | 134 | + acetyl esterase; Provisional | ||
| COG0657 | Aes | 2.0e-24 | 44 | 301 | 266 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 1.0e-46 | 76 | 298 | 230 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABB89008.1 | 0 | 1 | 317 | 1 | 338 | CXE carboxylesterase [Malus pumila] |
| GenBank | ACJ84311.1 | 0 | 1 | 317 | 3 | 328 | unknown [Medicago truncatula] |
| DDBJ | BAD80839.1 | 0 | 7 | 317 | 12 | 327 | 2-Hydroxyisoflavanone dehydratase [Glycyrrhiza echinata] |
| RefSeq | XP_002277880.1 | 0 | 3 | 318 | 4 | 317 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002517206.1 | 0 | 1 | 317 | 1 | 321 | catalytic, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o7v_A | 3e-35 | 25 | 286 | 29 | 300 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
| PDB | 2o7r_A | 3e-35 | 25 | 286 | 29 | 300 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_F | 3e-32 | 21 | 320 | 37 | 350 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_E | 3e-32 | 21 | 320 | 37 | 350 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_D | 3e-32 | 21 | 320 | 37 | 350 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CU608013 | 325 | 1 | 317 | 0 |
| EX285588 | 183 | 2 | 184 | 0 |
| ES789984 | 339 | 1 | 317 | 0 |
| EX528245 | 310 | 1 | 299 | 0 |
| JZ193031 | 279 | 2 | 273 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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