Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_131.52 |
Family | AA3 |
Protein Properties | Length: 572 Molecular Weight: 62549.5 Isoelectric Point: 9.8513 |
Chromosome | Chromosome/Scaffold: 131 Start: 388906 End: 392559 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 26 | 566 | 0 |
SSSSSFSSKGGDNAYDYIIVGGGTAGCPLAATLSQNFSVLLLERGGVPFTNANVSFLKNFHIGLADTSPTSASQAFVSTDGVINARARVLGGGSSINAGF YSRSGHRFIKSVGWDRKLVNESYPWVESQIVYQPKLALWQKAVRDGLLDVGVRPFNGFTYDHKYGTKIGGTIFDRFGRRHSAAELLSYANPQRLTVLIYA SVQRIIFDTSGKRPRAVGAIFKDENGKQHQALLRNTPGSEVILSCGAIGTPQLLMLSGIGPKKELEKFNISMVLDNEYVGKGMADNPMNSVFIPSKRPLE QSLIQTVGITNKGVYIEASSGFGQSSESIHCHHGIMSAELGQLSTIPPKQRTPEAIQAYIKGKKDLPHEAFRGGFILEKVANPLSTGHLKLITTNVEDNP SVAFNYFSHPLDLQRCVDGIRLAAKIVQSEHFTNYTQCDKQTVERLLNLSVKANVNFIPRHTNDTRSIEQFCKDTVITIWHYHGGCHVGLVVNHDLKVLG VPRLRIVDPSTFKQSPGTNPQATIMMMGRYMGVKILRERLG |
Full Sequence |
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Protein Sequence Length: 572 Download |
MGAGEKEVYE YKYPFIKRAS SFSPSSSSSS FSSKGGDNAY DYIIVGGGTA GCPLAATLSQ 60 NFSVLLLERG GVPFTNANVS FLKNFHIGLA DTSPTSASQA FVSTDGVINA RARVLGGGSS 120 INAGFYSRSG HRFIKSVGWD RKLVNESYPW VESQIVYQPK LALWQKAVRD GLLDVGVRPF 180 NGFTYDHKYG TKIGGTIFDR FGRRHSAAEL LSYANPQRLT VLIYASVQRI IFDTSGKRPR 240 AVGAIFKDEN GKQHQALLRN TPGSEVILSC GAIGTPQLLM LSGIGPKKEL EKFNISMVLD 300 NEYVGKGMAD NPMNSVFIPS KRPLEQSLIQ TVGITNKGVY IEASSGFGQS SESIHCHHGI 360 MSAELGQLST IPPKQRTPEA IQAYIKGKKD LPHEAFRGGF ILEKVANPLS TGHLKLITTN 420 VEDNPSVAFN YFSHPLDLQR CVDGIRLAAK IVQSEHFTNY TQCDKQTVER LLNLSVKANV 480 NFIPRHTNDT RSIEQFCKDT VITIWHYHGG CHVGLVVNHD LKVLGVPRLR IVDPSTFKQS 540 PGTNPQATIM MMGRYMGVKI LRERLGKAAG V* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
PRK02106 | PRK02106 | 3.0e-18 | 196 | 310 | 119 | + choline dehydrogenase; Validated |
pfam05199 | GMC_oxred_C | 4.0e-26 | 408 | 553 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. |
TIGR01810 | betA | 1.0e-31 | 41 | 553 | 565 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
COG2303 | BetA | 8.0e-46 | 40 | 564 | 577 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PLN02785 | PLN02785 | 0 | 3 | 571 | 569 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI35951.1 | 0 | 10 | 571 | 34 | 593 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002275841.1 | 0 | 10 | 571 | 25 | 584 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002327436.1 | 0 | 33 | 571 | 10 | 547 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329018.1 | 0 | 10 | 571 | 31 | 591 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 2 | 570 | 30 | 596 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 37 | 564 | 24 | 517 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
PDB | 3gdp_A | 0 | 37 | 564 | 24 | 517 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
PDB | 3gdn_B | 0 | 37 | 564 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 37 | 564 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 37 | 564 | 24 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO796743 | 532 | 41 | 572 | 0 |
EX273734 | 291 | 283 | 572 | 0 |
HO852522 | 376 | 192 | 567 | 0 |
ES808127 | 413 | 137 | 541 | 0 |
CK271873 | 317 | 38 | 354 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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