Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_136.66 |
Family | GT47 |
Protein Properties | Length: 540 Molecular Weight: 61161.7 Isoelectric Point: 9.0024 |
Chromosome | Chromosome/Scaffold: 136 Start: 718599 End: 720806 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 207 | 488 | 0 |
EKMFKIYVYEEGEPPMFHNGPCKSIYSTEGRFINEMEKGKFHRTKNPDEALVYFLPFSVVMMVQYLYVPESTNTHSIGRAVVDYITLIANRYPFWNRSLG ADHFMLSCHDWGPRASSYVPNLFNNSIRVLCNANTSEGFNPAKDASFPEINLITGEINGLLGGESPSRRPILAFFAGRLHGHIRHLLLQQWKDKDDDVQV YDHLPEGESYTSKLKKSKFCLCPSGYEVASPRVVEAIYAECVPVLISESYTAPFSDVLNWKAFSVEVKVEDIPNIKKILGSI |
Full Sequence |
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Protein Sequence Length: 540 Download |
MRTPQKKSYL SSSIFSSSFW LLYLLLPLSL LIFLLFKLPP DFSSWSSLSS SLTGRFDFSP 60 SNLSFTSSSS SSSSSLVLQL ASNNVNASIT INGSSSDANS FTLPANPAPA IYVISNNAST 120 NTSDTCTPEI LKEEKIPQNG EINVVKETTR VGRLEKLESR LSRVRSSIRE AALVRNLTSL 180 HADPDYVPWG SIYRNPNSFH RSYLEMEKMF KIYVYEEGEP PMFHNGPCKS IYSTEGRFIN 240 EMEKGKFHRT KNPDEALVYF LPFSVVMMVQ YLYVPESTNT HSIGRAVVDY ITLIANRYPF 300 WNRSLGADHF MLSCHDWGPR ASSYVPNLFN NSIRVLCNAN TSEGFNPAKD ASFPEINLIT 360 GEINGLLGGE SPSRRPILAF FAGRLHGHIR HLLLQQWKDK DDDVQVYDHL PEGESYTSKL 420 KKSKFCLCPS GYEVASPRVV EAIYAECVPV LISESYTAPF SDVLNWKAFS VEVKVEDIPN 480 IKKILGSISQ RQYLKMQRRV KEVQRHFVVN STPKRFDFFH MTLHSVWLRR LNVRIQDKN* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-52 | 206 | 488 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAU04753.1 | 0 | 201 | 537 | 7 | 343 | EXO [Cucumis melo] |
EMBL | CBI28483.1 | 0 | 176 | 537 | 55 | 416 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002264076.1 | 0 | 206 | 537 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002320538.1 | 0 | 206 | 537 | 1 | 332 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524591.1 | 0 | 140 | 537 | 106 | 504 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |