Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_17.165 |
Family | GT20 |
Protein Properties | Length: 494 Molecular Weight: 55106.9 Isoelectric Point: 6.6302 |
Chromosome | Chromosome/Scaffold: 17 Start: 2025671 End: 2033513 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 14 | 116 | 0 |
SIADVALVTSLRDGMNLVSYEFVACQASKKGVLILSEFAGAAQSLGAGALLVNPWNITEVAASIGYALNMPADEREKRHHHNFMYVTTHTSQEWAATFVS ELN |
Full Sequence |
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Protein Sequence Length: 494 Download |
MAPVARLHQH STRSIADVAL VTSLRDGMNL VSYEFVACQA SKKGVLILSE FAGAAQSLGA 60 GALLVNPWNI TEVAASIGYA LNMPADEREK RHHHNFMYVT THTSQEWAAT FVSELNDTIV 120 EAQLRTRQVP PLLPMKIAVD RYLQSNNRLL ILGFNATLTQ PANTLGRRGD QIREMELKLH 180 PDLREPLKNL CDDPKTTTVV ISGSDRSVLD DNFGEYNMWL AAENGMFLRL TTGEWMTTMP 240 ENLTMDWVDS VKHVFEYFTE RTPRSHFELR ETSLLWNYKY ADVEFGRLQA RDMLQHLWTG 300 PISNAALDVV QGSRSVEVRA VGVTKGAAID RILGEIVHNK GLKAPIDYVL CVGHFLGKDE 360 DVYTFFEPEL PCEILPAIRT KVADPVVAPI PHNSLSKTAR LKKQRSLSTL ERRSVNPVVR 420 GAWRPIMRDK VSLHEGSSVL DLKSENYFSC SVGRKQSSAR YLLGSSDDVV ALIKDLAECS 480 SEVECLGEEQ RGA* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam02358 | Trehalose_PPase | 2.0e-73 | 166 | 371 | 207 | + Trehalose-phosphatase. This family consist of trehalose-phosphatases EC:3.1.3.12 these enzyme catalyze the de-phosphorylation of trehalose-6-phosphate to trehalose and orthophosphate. The aligned region is present in trehalose-phosphatases and comprises the entire length of the protein it is also found in the C-terminus of trehalose-6-phosphate synthase EC:2.4.1.15 adjacent to the trehalose-6-phosphate synthase domain - pfam00982. It would appear that the two equivalent genes in the E. coli otsBA operon otsA the trehalose-6-phosphate synthase and otsB trehalose-phosphatase (this family) have undergone gene fusion in most eukaryotes. Trehalose is a common disaccharide of bacteria, fungi and invertebrates that appears to play a major role in desiccation tolerance. | ||
PRK14501 | PRK14501 | 1.0e-75 | 15 | 333 | 321 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
PLN03064 | PLN03064 | 0 | 14 | 481 | 477 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 14 | 477 | 464 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAK44102.2 | 0 | 14 | 481 | 68 | 552 | AF370287_1 putative trehalose-6-phosphate synthase [Arabidopsis thaliana] |
EMBL | CBI30769.1 | 0 | 14 | 480 | 61 | 484 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002305707.1 | 0 | 14 | 481 | 430 | 897 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331300.1 | 0 | 14 | 481 | 451 | 922 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522296.1 | 0 | 14 | 481 | 446 | 913 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1uqu_B | 2e-18 | 3 | 127 | 332 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqu_A | 2e-18 | 3 | 127 | 332 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqt_B | 2e-18 | 3 | 127 | 332 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqt_A | 2e-18 | 3 | 127 | 332 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 2wtx_D | 2e-18 | 3 | 127 | 332 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES813375 | 359 | 14 | 372 | 0 |
DV705833 | 283 | 84 | 366 | 0 |
FY436130 | 260 | 119 | 378 | 0 |
FY441598 | 259 | 120 | 378 | 0 |
JG627405 | 260 | 128 | 386 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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