| Basic Information | |
|---|---|
| Species | Carica papaya |
| Cazyme ID | evm.model.supercontig_18.158 |
| Family | CE10 |
| Protein Properties | Length: 343 Molecular Weight: 37772.9 Isoelectric Point: 5.3548 |
| Chromosome | Chromosome/Scaffold: 18 Start: 1438549 End: 1439577 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 30 | 315 | 0 |
| NRYNHTPNVQPSDSDSTLLTLSKDIPLNHANNTFIRLFMPKNIPPNTKLPLIIFFHGGGFVLFSVASLPYHESCIQMAAQISALILSVEYRLAPEHRLPA AYDDAVDSVMWVRNQAMDIDGCDSWLRDHADFSKCFLMGSSAGGNMVYHAALRAVDVDLSPLQIAGLILNQPYFGGVERTESEMRFVNDRILPLPANDLL WSLALPDGADRDHEYSNPMACEGGSCGEKIGRLQRCLVTGYGGDPLLDRQKEAVKMLESRGVHVETRFDHDGFHAVELFDPVRARG | |||
| Full Sequence |
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| Protein Sequence Length: 343 Download |
| MADNTPIAPS DSSIPNEFLK ITLNPDGSFN RYNHTPNVQP SDSDSTLLTL SKDIPLNHAN 60 NTFIRLFMPK NIPPNTKLPL IIFFHGGGFV LFSVASLPYH ESCIQMAAQI SALILSVEYR 120 LAPEHRLPAA YDDAVDSVMW VRNQAMDIDG CDSWLRDHAD FSKCFLMGSS AGGNMVYHAA 180 LRAVDVDLSP LQIAGLILNQ PYFGGVERTE SEMRFVNDRI LPLPANDLLW SLALPDGADR 240 DHEYSNPMAC EGGSCGEKIG RLQRCLVTGY GGDPLLDRQK EAVKMLESRG VHVETRFDHD 300 GFHAVELFDP VRARGLYERF KEFIRAACGS CNVSGVKAQS AI* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00312 | Esterase_lipase | 0.0003 | 66 | 173 | 115 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| COG2272 | PnbA | 4.0e-5 | 74 | 173 | 106 | + Carboxylesterase type B [Lipid metabolism] | ||
| PRK10162 | PRK10162 | 3.0e-9 | 65 | 294 | 233 | + acetyl esterase; Provisional | ||
| COG0657 | Aes | 2.0e-31 | 64 | 327 | 265 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 2.0e-58 | 81 | 304 | 224 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN60859.1 | 0 | 1 | 333 | 1 | 336 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_566047.1 | 0 | 8 | 340 | 3 | 327 | hydrolase [Arabidopsis thaliana] |
| RefSeq | XP_002277011.1 | 0 | 1 | 333 | 1 | 336 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002277119.1 | 0 | 1 | 324 | 1 | 324 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320078.1 | 0 | 15 | 334 | 3 | 324 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o7v_A | 0 | 4 | 330 | 3 | 333 | A Chain A, Crystal Structure Of A Beta-Galactosidase From Bacteroides Thetaiotaomicron |
| PDB | 2o7r_A | 0 | 4 | 330 | 3 | 333 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_F | 8e-37 | 71 | 295 | 105 | 317 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_E | 8e-37 | 71 | 295 | 105 | 317 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_D | 8e-37 | 71 | 295 | 105 | 317 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DY288919 | 317 | 15 | 328 | 0 |
| EC957007 | 275 | 60 | 333 | 0 |
| DY274643 | 318 | 15 | 329 | 0 |
| DY265785 | 330 | 15 | 332 | 0 |
| DY265342 | 318 | 15 | 329 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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