| Basic Information | |
|---|---|
| Species | Carica papaya |
| Cazyme ID | evm.model.supercontig_3.250 |
| Family | GH29 |
| Protein Properties | Length: 490 Molecular Weight: 55001.5 Isoelectric Point: 8.097 |
| Chromosome | Chromosome/Scaffold: 3 Start: 1783359 End: 1785045 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 43 | 341 | 0 |
| QLQWQQREIIMFLHFGVNTFTDSEWGTGHESPRVFNPVGLNATQWVNSAADAGVSLLILTAKHHDGFCLWPSKYTDHSVIGSPWKNGKGDVVLELVNAAR AHPGVDIGLYLSPWDRHDRRYGNNLLYNEFYLAQLQELLTKYGGVREIWFDGAKGKNAPNMSYEFEDWFSMVKELQSSINIFSDAGPNVRWVGNERGFAG STCWSTINRTMLSIGNASIVDYLNTGDPKGTDWLPAECDVSIRPGWFWHKSQTPKTLSDLLQIYYNSVGRNCLLLLNVPPNSTGLISEVDVRRLGEFRE | |||
| Full Sequence |
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| Protein Sequence Length: 490 Download |
| MANLWCLLWA TITFFQLCKP AISDREQVPT PPLPLLPLPS FSQLQWQQRE IIMFLHFGVN 60 TFTDSEWGTG HESPRVFNPV GLNATQWVNS AADAGVSLLI LTAKHHDGFC LWPSKYTDHS 120 VIGSPWKNGK GDVVLELVNA ARAHPGVDIG LYLSPWDRHD RRYGNNLLYN EFYLAQLQEL 180 LTKYGGVREI WFDGAKGKNA PNMSYEFEDW FSMVKELQSS INIFSDAGPN VRWVGNERGF 240 AGSTCWSTIN RTMLSIGNAS IVDYLNTGDP KGTDWLPAEC DVSIRPGWFW HKSQTPKTLS 300 DLLQIYYNSV GRNCLLLLNV PPNSTGLISE VDVRRLGEFR EAIDKIFSVN LAETCSIKAS 360 SQRGGKNGGF GPENVVDGDH LWTYWAPRDD EKGGNWIEIR GPDEGLRFNV VRIQEAIGLG 420 QRIQRHEIHV DGKKVVSGST VGYKRLHRLG KGGVVRGRHV RILVKKSKGL PLISSIGLHF 480 DPYWHPKEH* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 4.0e-26 | 53 | 339 | 320 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 5.0e-28 | 77 | 343 | 291 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 1.0e-59 | 43 | 444 | 413 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 42 | 486 | 22 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 30 | 486 | 7 | 461 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 1 | 488 | 1 | 484 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 1 | 486 | 1 | 483 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 1 | 486 | 1 | 483 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 39 | 474 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 39 | 474 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 39 | 474 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 39 | 474 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3eyp_B | 0 | 34 | 479 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX044171 | 294 | 136 | 427 | 0 |
| HE642643 | 343 | 1 | 341 | 0 |
| CO118382 | 292 | 5 | 294 | 0 |
| EY198039 | 318 | 169 | 484 | 0 |
| DR921868 | 299 | 188 | 486 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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