Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_30.157 |
Family | GT47 |
Protein Properties | Length: 455 Molecular Weight: 51796.4 Isoelectric Point: 8.2602 |
Chromosome | Chromosome/Scaffold: 30 Start: 1993671 End: 1997588 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 68 | 378 | 0 |
KVKVYMYDLPTRFTFGIIQQHAIARGASKDSVADLSTLKYPGHQHMHEWYLFADLNRPEKERVGSPVIRVMDPSEADLFYVPVFSSLSLIVNAGRPAGSG YSDEEMQDSLVEWLEKQQWWGRNNGWDHVIIAGDPNAMYRVVDRVKNAVLLVADFGRLRPDQGSLVKDVIIPYSHRISAYTGELGVENRDTLLFFMGNRY RKDGGKVRDLLFQVLESEEDVVIKHGTQSRENRRAASKGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKFSIFVHTDAALE PGCLVKMLRKV |
Full Sequence |
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Protein Sequence Length: 455 Download |
MARKSSFLKK ALIFVLLFIV AIYVFFNSVF NSSLPFNIPD FDPTLTVVDR SQAFAEIRHD 60 FSGNQSPKVK VYMYDLPTRF TFGIIQQHAI ARGASKDSVA DLSTLKYPGH QHMHEWYLFA 120 DLNRPEKERV GSPVIRVMDP SEADLFYVPV FSSLSLIVNA GRPAGSGYSD EEMQDSLVEW 180 LEKQQWWGRN NGWDHVIIAG DPNAMYRVVD RVKNAVLLVA DFGRLRPDQG SLVKDVIIPY 240 SHRISAYTGE LGVENRDTLL FFMGNRYRKD GGKVRDLLFQ VLESEEDVVI KHGTQSRENR 300 RAASKGMHTS KFCLNPAGDT PSACRLFDSI VSLCVPVIVS DSIELPFEDV IDYRKFSIFV 360 HTDAALEPGC LVKMLRKVSP KRIIEYQKQM TEVRRYYDYT NPNGTVNEIW RQVSQKLPLI 420 KLMINRDKRL VKREMTEPDC SCMCSNTTGI VSSF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-76 | 65 | 378 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_199306.1 | 0 | 10 | 451 | 14 | 440 | ARAD2 (ARABINAN DEFICIENT 2); catalytic [Arabidopsis thaliana] |
RefSeq | NP_850241.1 | 0 | 67 | 454 | 58 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002318294.1 | 0 | 73 | 454 | 1 | 382 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 1 | 454 | 1 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 1 | 454 | 1 | 452 | catalytic, putative [Ricinus communis] |