| Basic Information | |
|---|---|
| Species | Carica papaya |
| Cazyme ID | evm.model.supercontig_35.39 |
| Family | GH89 |
| Protein Properties | Length: 337 Molecular Weight: 39390.5 Isoelectric Point: 4.6284 |
| Chromosome | Chromosome/Scaffold: 35 Start: 774975 End: 778106 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH89 | 1 | 323 | 0 |
| MSMEGIEQNPIVYDLMSEMAFRHKNIDVKAWVGLYSMRRYGKSIPLIQDAWNILYHTVYNCTDGSYDKNRDVIVAFPDVDPFFISSPHKMHYCFGKPISR GASLREQKDSHDQPHLWYSLSEAIYALELFIACGEELAESSTYRYDLVDLTRQALAKYANQLFLDVIEAYQLNDVQEVALLSERFLELVDDLDLLLACHD GFLLGPWLESAKQLAQDEEQEKQFEWNARTQVTMWFDNTEEEASLLRDYGNKYWSGLLQDYYGPRAGLYFKYLIESLENGHVFPLKDWRREWIKLTNDWQ KRRNTFPVESVGDALSLACLLYE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 337 Download |
| MSMEGIEQNP IVYDLMSEMA FRHKNIDVKA WVGLYSMRRY GKSIPLIQDA WNILYHTVYN 60 CTDGSYDKNR DVIVAFPDVD PFFISSPHKM HYCFGKPISR GASLREQKDS HDQPHLWYSL 120 SEAIYALELF IACGEELAES STYRYDLVDL TRQALAKYAN QLFLDVIEAY QLNDVQEVAL 180 LSERFLELVD DLDLLLACHD GFLLGPWLES AKQLAQDEEQ EKQFEWNART QVTMWFDNTE 240 EEASLLRDYG NKYWSGLLQD YYGPRAGLYF KYLIESLENG HVFPLKDWRR EWIKLTNDWQ 300 KRRNTFPVES VGDALSLACL LYEKYLRSPG INYLDH* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05089 | NAGLU | 5.0e-5 | 1 | 23 | 23 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| pfam12972 | NAGLU_C | 4.0e-91 | 30 | 325 | 296 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI15090.1 | 0 | 1 | 331 | 509 | 843 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001054095.1 | 0 | 1 | 326 | 180 | 509 | Os04g0650900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002280399.1 | 0 | 1 | 331 | 476 | 810 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318632.1 | 0 | 1 | 329 | 479 | 807 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511461.1 | 0 | 1 | 336 | 475 | 809 | alpha-n-acetylglucosaminidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 1e-33 | 1 | 325 | 573 | 877 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
| PDB | 2vcb_A | 1e-33 | 1 | 325 | 573 | 877 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
| PDB | 2vca_A | 1e-33 | 1 | 325 | 573 | 877 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
| PDB | 2vc9_A | 1e-33 | 1 | 325 | 573 | 877 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 3e-33 | 1 | 325 | 596 | 900 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
 | ||||
| Hit | Length | Start | End | EValue |
| HO783128 | 292 | 1 | 292 | 0 |
| DR918913 | 277 | 59 | 331 | 0 |
| GT039480 | 290 | 1 | 287 | 0 |
| GT049437 | 292 | 38 | 326 | 0 |
| GT044006 | 292 | 38 | 326 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
