Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_38.66 |
Family | GT47 |
Protein Properties | Length: 420 Molecular Weight: 47837.5 Isoelectric Point: 7.0336 |
Chromosome | Chromosome/Scaffold: 38 Start: 1410483 End: 1413937 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 52 | 347 | 0 |
RLKVYVYELPSKYNKKLLQKDPRCLTHMFAAEIFMHRFLLSSPVRTLDPEEADWFYTPIYTTCDLTPTGLPLPFKSPRMMRSAIQLISTNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIERGILPLLQRATLVQTFGQRNHVCLNEGSITIPPYAPPQKMKAHLIRPDTPRSIFVYFRGLFYDVNNDPEGGYYARGA RAAVWENFKNNNLFDISTDHPTMYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVEEDDVPKLDSILTSI |
Full Sequence |
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Protein Sequence Length: 420 Download |
MGVAGKRMTI WIWVLIVFAV CLSWKISAED NVRTERISGS AGDVLEDDPV GRLKVYVYEL 60 PSKYNKKLLQ KDPRCLTHMF AAEIFMHRFL LSSPVRTLDP EEADWFYTPI YTTCDLTPTG 120 LPLPFKSPRM MRSAIQLIST NWPYWNRTEG ADHFFVVPHD FGACFHYQEE KAIERGILPL 180 LQRATLVQTF GQRNHVCLNE GSITIPPYAP PQKMKAHLIR PDTPRSIFVY FRGLFYDVNN 240 DPEGGYYARG ARAAVWENFK NNNLFDISTD HPTMYYEDMQ RAIFCLCPLG WAPWSPRLVE 300 AVVFGCIPVI IADDIVLPFA DAIPWEEIGV FVEEDDVPKL DSILTSIPVE VILRKQRLLA 360 NPSMKRAMLF PQPAQPGDAF HQILNGLARK LPHEKSIYLK PGKAILNWTV GPVGDLKPW* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-81 | 52 | 347 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33320.1 | 0 | 7 | 419 | 2 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | NP_174064.1 | 0 | 27 | 419 | 20 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | XP_002297880.1 | 0 | 7 | 419 | 2 | 412 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002304637.1 | 0 | 27 | 419 | 21 | 413 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511079.1 | 0 | 8 | 419 | 1 | 417 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |