| Basic Information | |
|---|---|
| Species | Carica papaya |
| Cazyme ID | evm.model.supercontig_4.186 |
| Family | CE10 |
| Protein Properties | Length: 329 Molecular Weight: 36341.5 Isoelectric Point: 5.5424 |
| Chromosome | Chromosome/Scaffold: 4 Start: 3310298 End: 3311284 |
| Description | carboxyesterase 20 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 37 | 321 | 0 |
| KIPSAPDFTHTAPVLTKDIPISPSNNTWFRLYLPTTALTSFSSDNKLPLIVYFHGGGFVLCSAEHSIFDDFCANLATDLHLIVASVEYRLAPEHRLPAAY DDAMESLHCIKTIEDDWLKRYADFSKCFIMGISAGGNIAYQVGLRAADAVDDVSPIKIRGLILQQPFFGGVERTGSELRLMNDPRLPPIVCDLMWDLSLP VGVDRDHEYSNPRASTGLENVKKLGWRVLVTGCDGDPLIDRQIELVKIMKERGVEAVGHFSVGDYHGVEVMEPSKAKKSHAVIKD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 329 Download |
| MSDQTHPSPP IVDPYQYLQI IPNPDGTITR NFNSFPKIPS APDFTHTAPV LTKDIPISPS 60 NNTWFRLYLP TTALTSFSSD NKLPLIVYFH GGGFVLCSAE HSIFDDFCAN LATDLHLIVA 120 SVEYRLAPEH RLPAAYDDAM ESLHCIKTIE DDWLKRYADF SKCFIMGISA GGNIAYQVGL 180 RAADAVDDVS PIKIRGLILQ QPFFGGVERT GSELRLMNDP RLPPIVCDLM WDLSLPVGVD 240 RDHEYSNPRA STGLENVKKL GWRVLVTGCD GDPLIDRQIE LVKIMKERGV EAVGHFSVGD 300 YHGVEVMEPS KAKKSHAVIK DFLSSASI* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00312 | Esterase_lipase | 5.0e-5 | 78 | 128 | 52 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| pfam00135 | COesterase | 2.0e-5 | 67 | 128 | 66 | + Carboxylesterase family. | ||
| COG2272 | PnbA | 6.0e-7 | 82 | 175 | 106 | + Carboxylesterase type B [Lipid metabolism] | ||
| COG0657 | Aes | 2.0e-30 | 66 | 326 | 267 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 8.0e-53 | 86 | 303 | 219 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ84396.1 | 0 | 1 | 324 | 1 | 325 | unknown [Medicago truncatula] |
| RefSeq | NP_201024.1 | 0 | 10 | 325 | 6 | 325 | AtCXE20 (Arabidopsis thaliana carboxyesterase 20); carboxylesterase |
| RefSeq | XP_002322442.1 | 0 | 1 | 326 | 1 | 330 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510874.1 | 0 | 1 | 328 | 1 | 331 | Gibberellin receptor GID1, putative [Ricinus communis] |
| RefSeq | XP_002510875.1 | 0 | 20 | 324 | 18 | 325 | Gibberellin receptor GID1, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o7v_A | 0 | 3 | 323 | 7 | 327 | A Chain A, Crystal Structure Of The Precursor Of Galactose Oxidase |
| PDB | 2o7r_A | 0 | 3 | 323 | 7 | 327 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 2zsi_A | 4e-31 | 19 | 291 | 39 | 315 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 2zsh_A | 4e-31 | 19 | 291 | 39 | 315 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 3ed1_F | 1e-30 | 74 | 325 | 103 | 349 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| JZ152128 | 312 | 14 | 322 | 0 |
| CK254196 | 320 | 1 | 312 | 0 |
| CK266032 | 313 | 7 | 314 | 0 |
| CK264049 | 322 | 7 | 323 | 0 |
| CK269459 | 311 | 1 | 303 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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