Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_40.36 |
Family | GT47 |
Protein Properties | Length: 703 Molecular Weight: 80992.8 Isoelectric Point: 9.2469 |
Chromosome | Chromosome/Scaffold: 40 Start: 646557 End: 650744 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 372 | 653 | 0 |
TLKVYVYKDGKKPIFHQPILKGLYASEGWFMKLMEGNKHFLVKDPRRAHLFYMPFSSRMLEYTLYVRNSHNRTNLRQYLKDYAENIAARYPYWNRTGGAD HFLVACHDWAPYETRHHMEYCIKALCNADVTAGFKIGRDVSLPETYVRAARNPLRDLGGKPHSQRRILAFYAGNMHGYLRPILLKHWKDKDASMKIFGPM PSGVASKMNYIQHMKSSKYCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVLNWSRFSIILAEKDIPNLKEILVSI |
Full Sequence |
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Protein Sequence Length: 703 Download |
MELLCQFRKL YQNEKRRWLF LVGIVAVTHL MFQSLLLPYG NALRSLLPDG CAPVFDESSR 60 LPSSTKSVMV RNPLAVNVSR KIDDSISAGM EIDNNITELG IGEGIGRESG LRDREKENGV 120 ASQELHLDNI IRFSSERNVI NDSLSENDDL NEMIALNSDE DQDDSSILEI TGETTLELPM 180 EQIGNPNQHI TMENHTSQLP RELNVNTRLQ FPFKPSLEVP SLQDSPYSNN SASNGASLQD 240 NLPKTSLNVP SLQKSTYFNN LVSNVASLQG NLPSVKRNST IISNIGKRKM RCEMPPKSVT 300 TIDEMNQILL RNRRSSRSMQ RPRWSSKRDE EILAARSQIE NALSIVDDPE LYAPAFRNVS 360 IFKRSYELMI QTLKVYVYKD GKKPIFHQPI LKGLYASEGW FMKLMEGNKH FLVKDPRRAH 420 LFYMPFSSRM LEYTLYVRNS HNRTNLRQYL KDYAENIAAR YPYWNRTGGA DHFLVACHDW 480 APYETRHHME YCIKALCNAD VTAGFKIGRD VSLPETYVRA ARNPLRDLGG KPHSQRRILA 540 FYAGNMHGYL RPILLKHWKD KDASMKIFGP MPSGVASKMN YIQHMKSSKY CICPKGYEVN 600 SPRVVESIFY ECVPVIISDN FVPPFFEVLN WSRFSIILAE KDIPNLKEIL VSIPEEKYHE 660 MQLAVRKIQR HFLWHAKPEK YDLFHMTLHS IWYNRVFQIK RR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-65 | 373 | 653 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 1 | 698 | 710 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 137 | 700 | 75 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 290 | 702 | 199 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 294 | 702 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 1 | 702 | 1 | 676 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |