y
Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_51.142 |
Family | GT47 |
Protein Properties | Length: 272 Molecular Weight: 31634.6 Isoelectric Point: 9.0553 |
Chromosome | Chromosome/Scaffold: 51 Start: 1350272 End: 1351256 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 3 | 219 | 0 |
SHFITNDPTEADLFFMPFSIVEMRHDLRIGVEGIKDFVKNYVVNISQTYPYWNRTGGADHFYVACHSSSRSAMEKINEVMSLTRMLPCPKFGLDLEIPPN LHTSERKQLAFFAGQINSPVRAALVKIWRNDTDIFAHFGRFKKPYGYQLMRSKFCLHVKVFEVNTAHISDALYYGCVPIIIADRHDLPFADILNWNSFSV VVAAVDIPVLKRVLQRI |
Full Sequence |
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Protein Sequence Length: 272 Download |
MHSHFITNDP TEADLFFMPF SIVEMRHDLR IGVEGIKDFV KNYVVNISQT YPYWNRTGGA 60 DHFYVACHSS SRSAMEKINE VMSLTRMLPC PKFGLDLEIP PNLHTSERKQ LAFFAGQINS 120 PVRAALVKIW RNDTDIFAHF GRFKKPYGYQ LMRSKFCLHV KVFEVNTAHI SDALYYGCVP 180 IIIADRHDLP FADILNWNSF SVVVAAVDIP VLKRVLQRIS FDEYSWLQSN VLKVRKHFKW 240 NDPPVDHDAF YITMYELWLR RSSVRVPLMR V* 300 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-45 | 1 | 219 | 252 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 1 | 268 | 198 | 483 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 1 | 269 | 163 | 448 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 1 | 268 | 161 | 445 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 1 | 268 | 44 | 324 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 1 | 266 | 44 | 326 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES827236 | 278 | 6 | 266 | 0 |
DT765011 | 253 | 30 | 265 | 0 |
AM713821 | 248 | 34 | 264 | 0 |
DY943505 | 255 | 2 | 238 | 0 |
GW785018 | 247 | 30 | 258 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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