Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_522.3 |
Family | GT47 |
Protein Properties | Length: 628 Molecular Weight: 72235.8 Isoelectric Point: 8.7797 |
Chromosome | Chromosome/Scaffold: 522 Start: 20812 End: 24399 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 299 | 581 | 0 |
NMLKVYIYKEGKKPIMHMPVLKGIYASEGWFMKLLEVNKKFVVRNPGKAHLFYLPFSSRMLEETLYIRDSHSHKNLIQFLKEYLDLISARYPFWNRTEGA DHFLVACHDWAPAETRKFMANCIRALCNSDVKEGFVFGKDASLPETNVRVPQKPLRDLGGKPSSERKTLAFFAGKMHGYLRPILLQHWGGNKDPDMKIFG PLPKVKGQKNYIQFMKSSKYCICAKGYEVNSPRVVEAIFYECVPVIISDNFVPPFYEVLNWESFAVFVLEEDIPNLKKILLSI |
Full Sequence |
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Protein Sequence Length: 628 Download |
MGHELRSLLL VETRRLIWLM GFVFAVILMF QYVELPYGNV LTSLFSTDKV TAPTDSSSRT 60 DGALNNSEMI ANLNLDSDIV SKGSKQLNSS GFDEANNVKQ SSSEKMKNSL VDNVNHFDNI 120 SSVPSLDELR EDEQGFSPQS ETDDNDYTET ENTILISQSE RTLNDTFASL LHYQQKFVIK 180 RENIMKSTSK DNETLGKLQS NFTISGDNSS LTVDPKVNRN SVTPKSAVTT IAEMKKLLHQ 240 NHASHHSVTP RWSSAVDQDL TYARSQIENA PIIKNDPALY APLYWNISMF KRSYELMENM 300 LKVYIYKEGK KPIMHMPVLK GIYASEGWFM KLLEVNKKFV VRNPGKAHLF YLPFSSRMLE 360 ETLYIRDSHS HKNLIQFLKE YLDLISARYP FWNRTEGADH FLVACHDWAP AETRKFMANC 420 IRALCNSDVK EGFVFGKDAS LPETNVRVPQ KPLRDLGGKP SSERKTLAFF AGKMHGYLRP 480 ILLQHWGGNK DPDMKIFGPL PKVKGQKNYI QFMKSSKYCI CAKGYEVNSP RVVEAIFYEC 540 VPVIISDNFV PPFYEVLNWE SFAVFVLEED IPNLKKILLS IPEKRYREMQ MRVKRVQQHF 600 LWHSKPVKYD IFHMILHSVW YNRVFQV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-70 | 301 | 581 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 15 | 627 | 30 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 1 | 627 | 1 | 652 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 627 | 1 | 666 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 187 | 627 | 28 | 468 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 234 | 627 | 1 | 395 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |