y
Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_65.36 |
Family | GH29 |
Protein Properties | Length: 529 Molecular Weight: 59504.9 Isoelectric Point: 6.0556 |
Chromosome | Chromosome/Scaffold: 65 Start: 484301 End: 486641 |
Description | alpha-L-fucosidase 1 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH29 | 48 | 352 | 0 |
ILPLPSASQLNWQQASMSLFLHFGMNTFTDSEWGSGQEDPSVFNPTQFNATQWVQVAKDSGFSTVILTAKHHDGFCLWPSDYTNYSVRSSPWEKGNGDVM AELAAAAKEAGVGLGIYLSPWDRHEDCYGKTVEYNEFYLGQITELLTRYGEIKEVFLDGAKGKGAVDMDYLFDSWFSLIHQLQPAAVIFSDAGPDSRWVG DEAGVAGSTCWSLFNRSNAKIGDTDPKYSQGGDPWGHDWVPAECDVSIRPGWFWHASQVPKTALKLLDIYYKSSGRNCHLLLNVPPNTSGLISDEDTKVL REFSE |
Full Sequence |
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Protein Sequence Length: 529 Download |
MENHSKKKKS TIKTLTKTSN STLFLLLIFV SLLQNSHCAF PKPPPLPILP LPSASQLNWQ 60 QASMSLFLHF GMNTFTDSEW GSGQEDPSVF NPTQFNATQW VQVAKDSGFS TVILTAKHHD 120 GFCLWPSDYT NYSVRSSPWE KGNGDVMAEL AAAAKEAGVG LGIYLSPWDR HEDCYGKTVE 180 YNEFYLGQIT ELLTRYGEIK EVFLDGAKGK GAVDMDYLFD SWFSLIHQLQ PAAVIFSDAG 240 PDSRWVGDEA GVAGSTCWSL FNRSNAKIGD TDPKYSQGGD PWGHDWVPAE CDVSIRPGWF 300 WHASQVPKTA LKLLDIYYKS SGRNCHLLLN VPPNTSGLIS DEDTKVLREF SELRRSIFSN 360 NLAKKAILSA SSTRGGNDNS QFNPYNVLEE GIHTYWAPEE DQSSWVLYLD LHELESFNVL 420 QVQEPIEMGQ RVISFHLEII DDNGKWKKVI RGTTIGYQRL LQFPTVKSRQ LKFVIDESRA 480 DPLISYFGIY IDRFSILGSI SDTNSHTLYN KSQIYPHIQH NHSQISTM* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
smart00812 | Alpha_L_fucos | 3.0e-26 | 59 | 350 | 338 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
pfam01120 | Alpha_L_fucos | 2.0e-26 | 59 | 350 | 328 | + Alpha-L-fucosidase. | ||
COG3669 | COG3669 | 6.0e-57 | 53 | 490 | 457 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] |
Gene Ontology | |
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GO Term | Description |
GO:0004560 | alpha-L-fucosidase activity |
GO:0005975 | carbohydrate metabolic process |
GO:0007155 | cell adhesion |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_180377.2 | 0 | 42 | 508 | 28 | 493 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
Swiss-Prot | Q8GW72 | 0 | 42 | 508 | 28 | 493 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
RefSeq | XP_002276131.1 | 0 | 53 | 528 | 51 | 545 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002313533.1 | 0 | 53 | 495 | 15 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523703.1 | 0 | 53 | 497 | 64 | 509 | alpha-l-fucosidase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3ues_B | 0 | 52 | 485 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3ues_A | 0 | 52 | 485 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3mo4_B | 0 | 52 | 485 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
PDB | 3mo4_A | 0 | 52 | 485 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
PDB | 3uet_B | 0 | 52 | 485 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |