Basic Information | |
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Species | Carica papaya |
Cazyme ID | evm.model.supercontig_77.64 |
Family | GT20 |
Protein Properties | Length: 772 Molecular Weight: 87675.6 Isoelectric Point: 6.8208 |
Chromosome | Chromosome/Scaffold: 77 Start: 647780 End: 662139 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 95 | 563 | 0 |
NRQRLLVVANRLPVSAVRRGEDSWSLEISAGGLVSALLGVKEFEARWIGWAGVNVPDEVGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFH YLGLPQEDRLATTRSFQSQFAAYKKANQMFADVVNKHYEEGDVVWCHDYHLMFLPKCLKEYNSSMKVGWFLHTPFPSSEIHRTLPSRTELLRSVLAADLV GFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSDRFIRALEVREVQEHIKDLKERFSGRKVMLGVDRLDMIKGIPQKLLAFEKFLEE NPQWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDIALVTSLRDGMNLVSYEFVACQGAKKGVLI LSEFAGAAQSLGAGAILVNPWNITEVAASIGQALTMSAQEREKRHEHNFLHVTTHTAQEWAETFVSELN |
Full Sequence |
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Protein Sequence Length: 772 Download |
MPGNKYNTNS THIPQTRTGR LLREKELRDR RKSSWAASHS NEVTGNNRGT EFSDHDLRLG 60 EGENSRSYIE RFLEEAAAAR AQAEGCDRQD VRPYNRQRLL VVANRLPVSA VRRGEDSWSL 120 EISAGGLVSA LLGVKEFEAR WIGWAGVNVP DEVGQKALTK ALAEKRCIPV FLDEEIVHQY 180 YNGYCNNILW PLFHYLGLPQ EDRLATTRSF QSQFAAYKKA NQMFADVVNK HYEEGDVVWC 240 HDYHLMFLPK CLKEYNSSMK VGWFLHTPFP SSEIHRTLPS RTELLRSVLA ADLVGFHTYD 300 YARHFVSACT RILGLEGTPE GVEDQGRLTR VAAFPIGIDS DRFIRALEVR EVQEHIKDLK 360 ERFSGRKVML GVDRLDMIKG IPQKLLAFEK FLEENPQWRD KVVLLQIAVP TRTDVPEYQK 420 LTSQVHEIVG RINGRFGTLT AVPIHHLDRS LDFHALCALY AVTDIALVTS LRDGMNLVSY 480 EFVACQGAKK GVLILSEFAG AAQSLGAGAI LVNPWNITEV AASIGQALTM SAQEREKRHE 540 HNFLHVTTHT AQEWAETFVS ELNDTVVEAQ QRSSKVPPEL PQLDAIERYL QSNNRLLILG 600 FNATLTEPVD TPGRRGDQIK EMDLKLHPEL KGPLTALCSD PKTTIVVLSG SHRHVLDDNF 660 REYDMWLAAE NGMFLRLTKG DWMTTMPEHL NMEWVDSVKH VFEYFKERTP RSHFDVRETS 720 LVWNYKYADV EFGRLQARDM LQHLWTGPIS NASVDVVQGS RSVEVRAVGV TK 780 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03064 | PLN03064 | 0 | 1 | 772 | 773 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 96 | 772 | 677 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
pfam00982 | Glyco_transf_20 | 0 | 97 | 564 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
TIGR02400 | trehalose_OtsA | 0 | 98 | 564 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
PRK14501 | PRK14501 | 0 | 98 | 772 | 681 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABO61742.1 | 0 | 1 | 772 | 1 | 767 | trehalose-phosphate synthase 1 [Solanum lycopersicum] |
EMBL | CAA69879.1 | 0 | 1 | 772 | 1 | 767 | trehalose-6-phosphate synthase [Arabidopsis thaliana] |
RefSeq | NP_177979.1 | 0 | 1 | 772 | 1 | 767 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002331300.1 | 0 | 1 | 772 | 1 | 762 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531237.1 | 0 | 1 | 772 | 1 | 765 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 98 | 572 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 98 | 572 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 98 | 572 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 98 | 572 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 0 | 98 | 572 | 3 | 464 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CX546763 | 303 | 85 | 387 | 0 |
CV711307 | 294 | 95 | 388 | 0 |
DW069910 | 288 | 184 | 471 | 0 |
ES813375 | 314 | 459 | 772 | 0 |
CX545499 | 305 | 401 | 705 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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