| Basic Information | |
|---|---|
| Species | Carica papaya |
| Cazyme ID | evm.model.supercontig_776.2 |
| Family | GT47 |
| Protein Properties | Length: 311 Molecular Weight: 35272.6 Isoelectric Point: 9.3212 |
| Chromosome | Chromosome/Scaffold: 776 Start: 7457 End: 8513 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 17 | 250 | 2.4e-25 |
| FSSSSSSLYLSPTTLFLGYQKMRKPTSSSSPLPFSNLSTRSISRAVAELRALFPYWNRTLGADHFLISCSGLGRYGDRNVIELNKNSVIVSCFPTRPGNF IPHKDITLPPLAANLARRAGTGFLKYLGYVRSGWVKDPTWVKRLASHADILVESEPSDSSTYEERLTGSRFCLFEYEAGDVSPLGETMRFGWVPVLIADR PKQDLLLMDVLTWQKLAVFVGSTSGVQELKSVLS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 311 Download |
| MSLISRFALF FFTFFLFSSS SSSLYLSPTT LFLGYQKMRK PTSSSSPLPF SNLSTRSISR 60 AVAELRALFP YWNRTLGADH FLISCSGLGR YGDRNVIELN KNSVIVSCFP TRPGNFIPHK 120 DITLPPLAAN LARRAGTGFL KYLGYVRSGW VKDPTWVKRL ASHADILVES EPSDSSTYEE 180 RLTGSRFCLF EYEAGDVSPL GETMRFGWVP VLIADRPKQD LLLMDVLTWQ KLAVFVGSTS 240 GVQELKSVLS HAMEGLYDEL RESCMAASKH LEWNGKPQLH DAFHMLMYQL WIRRHTIRCV 300 QREWVFETAR * |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-11 | 59 | 249 | 220 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001774096.1 | 1e-34 | 65 | 298 | 111 | 350 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002282317.1 | 0 | 1 | 305 | 6 | 360 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311191.1 | 0 | 19 | 305 | 21 | 345 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002316258.1 | 0 | 21 | 305 | 23 | 339 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524235.1 | 0 | 48 | 305 | 89 | 337 | conserved hypothetical protein [Ricinus communis] |
