| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g10273.t1 |
| Family | GT47 |
| Protein Properties | Length: 825 Molecular Weight: 92749.7 Isoelectric Point: 7.6832 |
| Chromosome | Chromosome/Scaffold: 9 Start: 7622768 End: 7631007 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 329 | 685 | 0 |
| KRPLIYMYDLDPLFNTRMLQYRLVRTSCLHRMFRADNSSTFVTHGYSIETYFIELLMTSGHRTYDPEEADFFFVPLLVTCYFWPVLGWSDHPWFGMPLAI VRPHQGAFMYRDAKRWIQKTYPWWDRRGGKDHIWMTAHDEGACWLPTEIYNTSIILTHWGRMDDIHVSGTAWGYDNYSAPLQAWPPHVEGDWRDIYDGHP CYTPGKDLVIPLFKPPGHYAHSPLLGAPPLQRDILLYLRGDTGPYRAHWYSRGIRQRLAKLAYMHDWAEEHRIFVGEQFMIPGTYSEHLARSIFCVVAPG DGYSGRGEDAVLHGCIPLIIMDGVHAVFESIIDWSAFSIRIAESAVNEQLPQFLKSI | |||
| Full Sequence |
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| Protein Sequence Length: 825 Download |
| MQDLEKYPSW QTVVKEKQKV YHTGAPQHAL NASVLQGTDG GLFEFVMIES LKAVCEGHVC 60 KRKPVPWKPA PRGDKECPAT KYGACNGVGV CQHDFGLCMC QAGWKGPDCG VRDPRPCTHR 120 FRLPSDANQT VPMSHVGPDG RDRNWSVPGW TASRCAGYCD EDYGLCYCPP DTRLGRVPAA 180 QGSAPYTPPI KIGRVVGDTC KPSRDPANGN AKATWGSTDP DLIFGVGGWC DNETHPTREC 240 GCLVDGVEGY TCSVITDIFC LNQCSGHGDC LYGYCKCHEG WYGMDCARRR ASSAPIPKAA 300 FEDAFPKHHQ GVVSFPAAAR DPPPAPTRKR PLIYMYDLDP LFNTRMLQYR LVRTSCLHRM 360 FRADNSSTFV THGYSIETYF IELLMTSGHR TYDPEEADFF FVPLLVTCYF WPVLGWSDHP 420 WFGMPLAIVR PHQGAFMYRD AKRWIQKTYP WWDRRGGKDH IWMTAHDEGA CWLPTEIYNT 480 SIILTHWGRM DDIHVSGTAW GYDNYSAPLQ AWPPHVEGDW RDIYDGHPCY TPGKDLVIPL 540 FKPPGHYAHS PLLGAPPLQR DILLYLRGDT GPYRAHWYSR GIRQRLAKLA YMHDWAEEHR 600 IFVGEQFMIP GTYSEHLARS IFCVVAPGDG YSGRGEDAVL HGCIPLIIMD GVHAVFESII 660 DWSAFSIRIA ESAVNEQLPQ FLKSISPAQI ELMQRKIAMV WHRFAYATGP MMQDTLGATY 720 AANRVLRRHV RNLLPVNAVE VDTRHTLDTV RRLTRGGVLP APAWLGLDKV QGQNGTGLAW 780 QGQPDGEWLG PLGHPQRAYR RFPVLNDAWH TILAWLHSRI PSTR* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-46 | 333 | 685 | 354 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001696764.1 | 0 | 3 | 210 | 31 | 311 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001696764.1 | 0 | 262 | 723 | 304 | 821 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001696822.1 | 0 | 19 | 475 | 810 | 1267 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 61 | 824 | 90 | 800 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698801.1 | 0 | 50 | 824 | 131 | 942 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD867786 | 240 | 430 | 669 | 0 |
| BI816478 | 166 | 506 | 671 | 0 |
| FD884517 | 256 | 169 | 424 | 0 |
| BP097806 | 145 | 535 | 679 | 0 |
| FD801053 | 296 | 273 | 565 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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