| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g1252.t1 |
| Family | GT4 |
| Protein Properties | Length: 543 Molecular Weight: 56430.1 Isoelectric Point: 8.0018 |
| Chromosome | Chromosome/Scaffold: 1 Start: 7840560 End: 7847420 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT4 | 268 | 399 | 1.7e-21 |
| QLYLVSVNQFRPEKNHRLQLEAFAAAKRSPAAAAPTLAGAALREARLKLVGGVRGPADEARLAGLKAYAAELGIADSCEWIVNAPFSELRQLLGGAVAGL HTMTDEHFGISVVEYMAAGCVPIAHNSAGPKM | |||
| Full Sequence |
|---|
| Protein Sequence Length: 543 Download |
| MYTDALDSLL YLTAAALAAV IASVLLAFCV LMGVVAFFHP FADGGGGGER VLWCAVKAVH 60 DASKTAKVVI YCREGLSAAA LVEDAQRRFN IRIDKPIQVV PLRRVGLIQP ERYPRLTLVR 120 QALGSVALGW EALRQVVPEV YIDTTGWAFP YPLAWRAGAA VVAYVHYPTI SSDMLAAVWA 180 GSATAVSNDA DIAESPIKTA AKLLYYGALA GWYAGCGAVT RLAAVNSSWT RRHIAGLWRL 240 ARRPPVLVYP PVDTAELQTL PLDRKLKQLY LVSVNQFRPE KNHRLQLEAF AAAKRSPAAA 300 APTLAGAALR EARLKLVGGV RGPADEARLA GLKAYAAELG IADSCEWIVN APFSELRQLL 360 GGAVAGLHTM TDEHFGISVV EYMAAGCVPI AHNSAGPKMD IVLPLLLDAQ GAAALAAAAG 420 LGRGGSDSLG GCGGADGLLG PAADSPLVLD AGAHVSPAGA AGAGTCQAGG GGGGAVGGGA 480 VQVTGFLATT VDEYAEAIIK VLTMDQRERL RVAAAAQRQA GRFSTERFLQ DFTAALADVL 540 PP* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd03806 | GT1_ALG11_like | 0.004 | 486 | 531 | 46 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. | ||
| PLN02949 | PLN02949 | 1.0e-5 | 486 | 540 | 55 | + transferase, transferring glycosyl groups | ||
| cd03805 | GT1_ALG2_like | 1.0e-13 | 225 | 402 | 194 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. | ||
| PLN02949 | PLN02949 | 2.0e-132 | 34 | 402 | 370 | + transferase, transferring glycosyl groups | ||
| cd03806 | GT1_ALG11_like | 3.0e-162 | 34 | 402 | 372 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_181548.2 | 0 | 35 | 416 | 36 | 406 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | NP_181548.2 | 0.0000000004 | 482 | 540 | 400 | 458 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | XP_001700237.1 | 0 | 1 | 542 | 1 | 542 | glycosyl transferase; group 1 [Chlamydomonas reinhardtii] |
| RefSeq | XP_001780017.1 | 0 | 14 | 403 | 14 | 396 | predicted protein [Physcomitrella patens subsp. patens] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5464 | EC-2.4.1.131 | GDP-Man:Man3GlcNAc2-PP-Dol α-1,2-mannosyltransferase |
