| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g13296.t1 |
| Family | GT47 |
| Protein Properties | Length: 1385 Molecular Weight: 153950 Isoelectric Point: 7.5454 |
| Chromosome | Chromosome/Scaffold: 12 Start: 6845578 End: 6872944 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 786 | 965 | 4.7e-25 |
| KRPWVYVYELPPDLTTWTNTKRLDRSTHIHFYQRLLGSGARIADGDKADWYYIPIRQRMTADSRFLSEAVAYISATYPWWNRTGGSRHFVIHTGDLGADE TQLGARLQAPNITWLTHWGLTMDKVFSGWKKAHRPDKDVVIPVFLTPGHFKHFGLERTPLHPLMDKQERTTTFFFAGDLG | |||
| GT47 | 995 | 1167 | 7.4e-26 |
| SGWKKAHRPDKDVVIPVFLTPGHFKHFGLERTPLHPFMDKQERTTTFFFAGRICGDRKPPKTGSWPNCGPRSPGYSAGVRQLVHHHHWDPPGFKVVLHEP NYGAALGSSKFCLAPLGGGHGQRQIIVSFMGCLPVCIADDVYEPFEPQYNWTQFGVRPAESDIPELHTILESV | |||
| GT47 | 158 | 456 | 5.60519e-45 |
| KRPWVYVYELPPDLTTWTNTKRLDRSTHIHFYQRLLGSGARIADGDKADWYYIPIRQRMTADSRFLSEAVAYISATYPWWNRTGGSRHFVIHTGDLGADE TQLGARLQAPNITWLTHWGLTMDKVFSGWKKAHRPDKDVVIPVFLTPGHFKHFGLERTPLHPLMDKQERTTTFFFAGRICGDRKPPKTGSWPNCGPRSPG YSAGVRQLVHHHHWDRPGFKVVLHEPNYGAALGSSKFCLAPLGGGHGQRQIIVSFMGCLPVCIADDVYEPFEPQYNWTQFGVRPAESDIPELHTILESV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1385 Download |
| MTAVVLITIL CLLSGSINAH YNDDGGHLQG RLLRVDDDPV AAPTNFKSRC VGKCTQYGTC 60 NEDIARCDCP KNRTGDDCVD IADTDTLTSR CRRNYYPSVK ECTTSELSCL NNCNKRGTCV 120 SGWCHCKPGF FGADCSLSLD AEGKPELLAG TGYATRAKRP WVYVYELPPD LTTWTNTKRL 180 DRSTHIHFYQ RLLGSGARIA DGDKADWYYI PIRQRMTADS RFLSEAVAYI SATYPWWNRT 240 GGSRHFVIHT GDLGADETQL GARLQAPNIT WLTHWGLTMD KVFSGWKKAH RPDKDVVIPV 300 FLTPGHFKHF GLERTPLHPL MDKQERTTTF FFAGRICGDR KPPKTGSWPN CGPRSPGYSA 360 GVRQLVHHHH WDRPGFKVVL HEPNYGAALG SSKFCLAPLG GGHGQRQIIV SFMGCLPVCI 420 ADDVYEPFEP QYNWTQFGVR PAESDIPELH TILESVSAKE YAAKQRALRC AAQHFVYSSI 480 VGGLFGEDGR YDAFETTLEV LRVKAEHPDA APETYRQIDE DFDAFMDCRD PPRWKAAAPA 540 PHLWGLEDEE EDGEGEGEGE EVEKGSGAHR VQNGAEWAVA KEQMTMPGRR PAPLLLVALV 600 WALGCQLRVN AFFFRSKPAP KQHPEHPAPA LARAPAPAAA VGVPFTPGVS RCPANCSRFG 660 SCNEETGSCD CLRNRMGPDC GRKLMRPGML QRCQDMGYKD VKECLAKDQL CVNACNNRCR 720 RNYYPSVKEC TTSELSCLNN CNKRGTCVSG WCHCKPGFFG ADCSLSLDAE GKPELLAGTG 780 YATRAKRPWV YVYELPPDLT TWTNTKRLDR STHIHFYQRL LGSGARIADG DKADWYYIPI 840 RQRMTADSRF LSEAVAYISA TYPWWNRTGG SRHFVIHTGD LGADETQLGA RLQAPNITWL 900 THWGLTMDKV FSGWKKAHRP DKDVVIPVFL TPGHFKHFGL ERTPLHPLMD KQERTTTFFF 960 AGDLGADETQ LGARLQAPNI TWLTHWGLTM DKVFSGWKKA HRPDKDVVIP VFLTPGHFKH 1020 FGLERTPLHP FMDKQERTTT FFFAGRICGD RKPPKTGSWP NCGPRSPGYS AGVRQLVHHH 1080 HWDPPGFKVV LHEPNYGAAL GSSKFCLAPL GGGHGQRQII VSFMGCLPVC IADDVYEPFE 1140 PQYNWTQFGV RPAESDIPEL HTILESVSAK EYAAKQRALR CAAQHFVYSS IVGGLFGEDG 1200 RYDAFETTLE VLRVKAEHPD AAPETYRQID EDFDAFMDCR DPPRWKAAAP APHLWGLEDE 1260 EEDGEGEGEG EEVEKGSGRA NGSEVKPGRG RGKEGGGKAG RKGGWLGKVL GRSLLGGDEG 1320 AKVDSAGEQG GGWVNPLCSH SMMDRKWNPC ERFVQGASKT HMIPGGIMCA KTRHNLAECP 1380 RIWL* 1440 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-17 | 984 | 1167 | 189 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 7.0e-18 | 790 | 1003 | 228 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 1.0e-34 | 162 | 456 | 315 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001702686.1 | 0 | 38 | 528 | 62 | 553 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 958 | 1239 | 266 | 553 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 66 | 534 | 9 | 477 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 669 | 967 | 10 | 282 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 961 | 1245 | 193 | 477 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
