| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g13482.t1 |
| Family | GT41 |
| Protein Properties | Length: 1447 Molecular Weight: 147043 Isoelectric Point: 6.8407 |
| Chromosome | Chromosome/Scaffold: 12 Start: 7869735 End: 7881135 |
| Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT41 | 756 | 1185 | 0 |
| IRPHFPQSLNNLGVVLTAQGRAAEALALLSAAVAASPAYTEAHNNLGVLQRDVGCIPEALASYSRCLELDPRCRNAGQNRLLALNYIYPGESELVCSAHR EWGERFQADISPLPPLPPGAHSWDPERPLRVGYISPDLFTHSVSYFAEAPLSHHSPARGFTHIVYSCVPKPDAKTLRLRAATEAAGGVWREVAGLSEAEL AAAVRADGVDLLLELTGHTANNRLGVLARRPAPLQATWIGYPNSTGLAAVDYRLTDAVCDPYDTQQTFVEELVRLPGCFLCYTPAADAPPVAPPPCLHNG YITFGSFNNLAKITPQVLRVWAAILAAVPRSRLVLKNKPFACEAARSHLLRQLAALGVEGWRVDLLPLAPGNSQHLSQYALMDISLDPFPYAGTTTTTES LYMGVPTLTLAGRCHAHNVGVSLLTAVGLH | |||
| Full Sequence |
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| Protein Sequence Length: 1447 Download |
| MCPASVEQLK VEAGSAPADS AQNRDCGNQQ VPLRLLSGSP SLHNHTGDPG RYGSQPHMPS 60 SHPDSPASPN FRAQQSPQPL RQLPAKACEA SPELEQAVCD VGTAAAYGAA AATATAAAES 120 GRQKDDGAAV AGATACFNPS LPAPPLHAYD SLTLAQSNSN RQQQLQAQHQ QQLEQLLALQ 180 QQYQQQQPAA VSVGQAMPLL AAAAAAAAAA PVATLPYMQW GHAVLPAVDA PAAPAGGGGA 240 GARPAGGTST LPGVLTPEAG GVALSPFSPM AMGTPHAAAV APAGAAGAAG VAASPFAAAQ 300 APSTHMHVNV QGQGQNPGQQ VLAELGHAGA MAVSQVLDMQ QRLLQQVSVA QLQQPLLYVQ 360 PTQQQQQQQS IPFPQLAHQL GPSTLLPQPQ QLQLQPQQLH PQPPAATGAA APPATSMPAG 420 ALALAAAAAP AAAADADAAA AAQCRLAAVL RAGGKPAEAV ALLDVVLAQQ PARVEALFQR 480 AACQQALGQV HEAQATYLRA LAAAPDHTPS LTALGALYQA QGLLGEAVAA YQRAHELRPA 540 DGAIREGLAV VLTDQGTKLK NAGAPVSEAV SRYQAAAALC PCYAPALYNL GVVAGELRQA 600 DAAVEYYRAA IAAEPRYAQA HCNLGVLLRE RGRLPEAVAA YEAALAAAPN FTIVRNNLAI 660 ALTDLGTHVK NEGRLQEGIA LYERALSYAP RHADALYNLG VAYGEKGDLQ RAAFMYEMAL 720 AFNPACAEAH NNLGVIWKER DNVDKAVECY SAALAIRPHF PQSLNNLGVV LTAQGRAAEA 780 LALLSAAVAA SPAYTEAHNN LGVLQRDVGC IPEALASYSR CLELDPRCRN AGQNRLLALN 840 YIYPGESELV CSAHREWGER FQADISPLPP LPPGAHSWDP ERPLRVGYIS PDLFTHSVSY 900 FAEAPLSHHS PARGFTHIVY SCVPKPDAKT LRLRAATEAA GGVWREVAGL SEAELAAAVR 960 ADGVDLLLEL TGHTANNRLG VLARRPAPLQ ATWIGYPNST GLAAVDYRLT DAVCDPYDTQ 1020 QTFVEELVRL PGCFLCYTPA ADAPPVAPPP CLHNGYITFG SFNNLAKITP QVLRVWAAIL 1080 AAVPRSRLVL KNKPFACEAA RSHLLRQLAA LGVEGWRVDL LPLAPGNSQH LSQYALMDIS 1140 LDPFPYAGTT TTTESLYMGV PTLTLAGRCH AHNVGVSLLT AVGLHPLPPC GGAGSGGGAG 1200 GSPGSSGGGG TGGSGAGRSG APGLLPSGGS LDVSSGGGGG GGGGGGGGGG GGGGGGGGGG 1260 GGGGGGGGAS ACPTLPASPA GSGSSSPHTH SQAGSPVLQA SGQQASAPEA TTRQQQQQQQ 1320 QHAGSSSPGG CSGGGSGSGC GGGGGVGGLP GSVGCGASWV ARSEEEYVEL AAAHAANFQA 1380 LADLRAGLRG RMLASPMCDA PSFILRLEGV YRGLWRRHCA QMLGDAAAAA AAARSVGIDL 1440 SRRRGT* 1500 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG3914 | Spy | 0.0006 | 1359 | 1417 | 59 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] | ||
| cd00189 | TPR | 7.0e-14 | 619 | 724 | 106 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| cd00189 | TPR | 6.0e-15 | 694 | 776 | 83 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| cd00189 | TPR | 5.0e-19 | 661 | 759 | 99 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| COG3914 | Spy | 3.0e-68 | 858 | 1184 | 331 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001694146.1 | 0 | 417 | 1189 | 1 | 776 | O-linked N-acetylglucosamine transferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694146.1 | 2e-25 | 1359 | 1419 | 777 | 837 | O-linked N-acetylglucosamine transferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001782948.1 | 0 | 420 | 1187 | 2 | 765 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002530535.1 | 0 | 447 | 1184 | 56 | 788 | o-linked n-acetylglucosamine transferase, ogt, putative [Ricinus communis] |
| RefSeq | XP_002530535.1 | 0.0000001 | 1349 | 1419 | 782 | 851 | o-linked n-acetylglucosamine transferase, ogt, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4gz6_D | 2e-36 | 690 | 1035 | 6 | 386 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 4gz6_D | 5e-19 | 503 | 733 | 4 | 212 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 4gz6_D | 0.00000002 | 1057 | 1183 | 524 | 646 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 4gz6_D | 0.002 | 446 | 590 | 15 | 151 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DY295408 | 362 | 823 | 1178 | 0 |
| GO867600 | 327 | 716 | 1038 | 0 |
| CB673990 | 286 | 899 | 1184 | 0 |
| GO867600 | 100 | 659 | 758 | 0.0000000003 |
| GO867600 | 118 | 615 | 732 | 0.000007 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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