| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g6237.t1 |
| Family | GT47 |
| Protein Properties | Length: 814 Molecular Weight: 91401.7 Isoelectric Point: 7.4581 |
| Chromosome | Chromosome/Scaffold: 6 Start: 3442334 End: 3449293 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 373 | 729 | 0 |
| RPLIYVYDVPPDYTSRMLQYRNFGDTCLWRRWHDGNFTGITGYTYGIETLMHELMLQSEHRTFDPEEADFFYVPMYITCYFWPILGWADGPWWHAPNGLR VMHGANMITELHDWLRTKLPYWDRRGGRDHIWLMAADEGACWMPKAVYDTSIVLTHWGRLDPEHKSNTAYLQDNYTAKPESAFDAWRGVDFGDRIKGHPC FDPRKDLVVPAFKSPNHFPRSPLIGAPPLERDLLLFFRGDVGASRLPHYSRGIRQRLFHLAHKHDWYNRFKIAIGSGDSLKGDYSEQLARSKFCLVAPGD GWSPRAEDAILHGCIPVVVMDGVQAVFESILDWDSFSLRIREDDAALEALPQLLASI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 814 Download |
| MFARLRSRSQ RLLIVFGLAS GCVLVCLWRT AEATDGERRG LASGLRSLLH FEMPAGAHIS 60 LPDPPKVLVA AAEPEDNSTR PHHHHEMDPE AALRRRCALV KGTWCGEFLR QVRLPARPVP 120 RGRKECPNAC SGWGNCNHDT GMCECPAGHG GEDCSKPVKR PCAHRHRNIS NPNATEPVSS 180 VGPNGLDIGP TTVQGWTASR CFGFCDEDVA ACYCGEGRYA RIPPPPGSPP WTPPVQRGRP 240 LADGCQPNTD ATGAKSFAAG GGTSWADIYG PNGFCNDPNK ATRCGCFQEI AFPCDGSVPM 300 ETTCMNQCSG HGECHFGYCR CHKFWYGSDC SRKKADSGPL EPALHESERP WLRPVVAVPP 360 AALETPPIST RPRPLIYVYD VPPDYTSRML QYRNFGDTCL WRRWHDGNFT GITGYTYGIE 420 TLMHELMLQS EHRTFDPEEA DFFYVPMYIT CYFWPILGWA DGPWWHAPNG LRVMHGANMI 480 TELHDWLRTK LPYWDRRGGR DHIWLMAADE GACWMPKAVY DTSIVLTHWG RLDPEHKSNT 540 AYLQDNYTAK PESAFDAWRG VDFGDRIKGH PCFDPRKDLV VPAFKSPNHF PRSPLIGAPP 600 LERDLLLFFR GDVGASRLPH YSRGIRQRLF HLAHKHDWYN RFKIAIGSGD SLKGDYSEQL 660 ARSKFCLVAP GDGWSPRAED AILHGCIPVV VMDGVQAVFE SILDWDSFSL RIREDDAALE 720 ALPQLLASIS PERLAHMQRH LARVWHRFAY TQTPFLKATV DRTIHGYQHK LQEAKQEVLR 780 DAPYQPVAHY PHADDAFGTI MQWLFHRIPD TRG* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-49 | 371 | 729 | 361 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 93 | 812 | 80 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697121.1 | 0 | 90 | 813 | 96 | 802 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698039.1 | 0 | 37 | 813 | 53 | 810 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 40 | 812 | 21 | 800 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698801.1 | 0 | 97 | 812 | 133 | 942 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
