| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g6238.t1 |
| Family | GT47 |
| Protein Properties | Length: 758 Molecular Weight: 85002.8 Isoelectric Point: 6.9576 |
| Chromosome | Chromosome/Scaffold: 6 Start: 3449984 End: 3458225 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 282 | 639 | 0 |
| RRPLIYVYDVPPKYTSRMLQYRLLAHACLWRRWLDGNNTELTGWTYSVETMFHELLLQSEHRTFDPEEADFFYVPHYVTCYFWPIMGWADAPWWHAPYVD SRPMHGANMLTELHGWLRTNLPYWDRRGGRDHIWLMAADEGACWMPTAIYNTSIVLTHWGRLEANHTSGTAYLQDVYDRPVYGFQRWPGVDYHHDIEGHP CFDPKKDLVIPAFKPPFHFARSPLLGAPPLQRDILLYFRGDSGAFRLPQYSRGIRQRITDLSNRQDWFNRYKIVISHGGMVGGDYSEHLARSKFCLVAPG DGWSPRAEDAILHGCIPVVVMDGVQAVFESILDWDSFSLRIREDDAALEALPQLLASI | |||
| Full Sequence |
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| Protein Sequence Length: 758 Download |
| MPGNPHEAVR KRCALARGTW CGGWMRQDPL PYKAVPRGSK ECPNACSGWG NCNHDTGLCE 60 CPAGRDGDDC GKEFKRPCTD HHRGKGDVLR TEPASHIGPD GLDLDVTNLR WTASRCHGYC 120 DDNVAACYCG EGSLRRIPAP PGAPPWTPPV QHGRPLADGC QPATSKTGLK SWGQVKYDDI 180 YGPSGWCNNR TSAFECGCFQ EIAHPCDGSV PMETTCMNQC SGHGECHFGY CRCHTDWYGS 240 DCSRKKAGTP VEPPLQEQRP WLQQVTAQPP AANVLPLPGG RRRPLIYVYD VPPKYTSRML 300 QYRLLAHACL WRRWLDGNNT ELTGWTYSVE TMFHELLLQS EHRTFDPEEA DFFYVPHYVT 360 CYFWPIMGWA DAPWWHAPYV DSRPMHGANM LTELHGWLRT NLPYWDRRGG RDHIWLMAAD 420 EGACWMPTAI YNTSIVLTHW GRLEANHTSG TAYLQDVYDR PVYGFQRWPG VDYHHDIEGH 480 PCFDPKKDLV IPAFKPPFHF ARSPLLGAPP LQRDILLYFR GDSGAFRLPQ YSRGIRQRIT 540 DLSNRQDWFN RYKIVISHGG MVGGDYSEHL ARSKFCLVAP GDGWSPRAED AILHGCIPVV 600 VMDGVQAVFE SILDWDSFSL RIREDDAALE ALPQLLASIS PERLAHMQRH LARVWHRFAY 660 TTGPLLNRSV TEHYTARQSE FEAASKPPEE RQPDLRAIPA TPPDHPFQPL RRLPNSDDDA 720 FGTIMQWLFH RIPDTRGGDA GAAAAAAAAA AAAASAA* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-49 | 281 | 639 | 361 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 9 | 736 | 80 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697121.1 | 0 | 9 | 737 | 99 | 802 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698039.1 | 0 | 4 | 737 | 104 | 810 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 1 | 736 | 65 | 800 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698801.1 | 0 | 13 | 736 | 133 | 942 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| BI717917 | 219 | 264 | 482 | 0 |
| BI718248 | 218 | 267 | 483 | 0 |
| FD867786 | 241 | 383 | 623 | 0 |
| FD801053 | 291 | 229 | 518 | 0 |
| GE255396 | 262 | 406 | 661 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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