| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g6362.t1 |
| Family | GT47 |
| Protein Properties | Length: 683 Molecular Weight: 74837.8 Isoelectric Point: 7.9559 |
| Chromosome | Chromosome/Scaffold: 6 Start: 4100946 End: 4107847 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 300 | 621 | 0 |
| LKVYMYDIPISVVGPQPFDDGDATVYLIYQASMHLMNAFLADTGGVRTQNPWEANLFYVPTFAYFSTANLGDPTAAVVRAIDWVSSKFPFFARHGGRDHF VVLTADRGACYLKPLNQTRNLIRLVHFGLEKPNLTEMGPLVEEREYGCFKSGRDVVLAPYFRPKASVVRAVHEKLLAPGGAEELLKDKSVLFFFSGDVRH HEPEYSGGVRQALSALLSNTTTTTTGSGSGPAPPDDVVFKAGSQPITAEEYEQLLGRAKFCLAPYGHGWGIRLTHALMHACVPVIIQDRVRQPWEDLLHY PDFSIRVAKSQLPRLVELLRAV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 683 Download |
| MSRRLALLVL LFSVVLVLTQ AEDAVLKTAV EGKPFNVFQE LKKECDPGCQ QCNRELGECE 60 CPYGLSGPTC QVALWPACRT STAAGLPVFV GRRAPRNCHC YRQLFRATCL PGSESRCSSH 120 TVAHWPDLKC FEQPDKPEQE QLSELPDTLD DPAYRWRKGV LLPAPAGGTG VEGAAGGAAA 180 AEHKDFQTLP APPALKEIGD TVALGKCPNR CRDRGICIAN SETVKTPSCL CHPGFTGTDC 240 ADVVPPASLP LLCPNGCGGR GKCAAGFCAC DPPYWGIGCS RSKAYQPVPD SISHPYYPSL 300 KVYMYDIPIS VVGPQPFDDG DATVYLIYQA SMHLMNAFLA DTGGVRTQNP WEANLFYVPT 360 FAYFSTANLG DPTAAVVRAI DWVSSKFPFF ARHGGRDHFV VLTADRGACY LKPLNQTRNL 420 IRLVHFGLEK PNLTEMGPLV EEREYGCFKS GRDVVLAPYF RPKASVVRAV HEKLLAPGGA 480 EELLKDKSVL FFFSGDVRHH EPEYSGGVRQ ALSALLSNTT TTTTGSGSGP APPDDVVFKA 540 GSQPITAEEY EQLLGRAKFC LAPYGHGWGI RLTHALMHAC VPVIIQDRVR QPWEDLLHYP 600 DFSIRVAKSQ LPRLVELLRA VPAEDVARLM REGARVYRAF VWQPELGGLA YNYTIASLRR 660 RLSHIRGELY EAGTRRRRGR QL* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-31 | 298 | 621 | 328 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693329.1 | 0 | 61 | 670 | 2 | 599 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694919.1 | 0 | 43 | 670 | 11 | 674 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 38 | 661 | 23 | 671 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 28 | 661 | 31 | 695 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698067.1 | 0 | 40 | 171 | 1 | 132 | hypothetical protein CHLREDRAFT_95682 [Chlamydomonas reinhardtii] |
