| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g9612.t1 |
| Family | GT47 |
| Protein Properties | Length: 697 Molecular Weight: 78409.2 Isoelectric Point: 7.7021 |
| Chromosome | Chromosome/Scaffold: 9 Start: 3319110 End: 3326331 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 277 | 647 | 3.60134e-43 |
| RLKIYVYDLPESVVHMRSHSDEWPLHFPIYLAEHEFFNRLLGDWATRTENPWEANLFYIPTFTYYYIGNVGQPGKLFSRVVSYVRHNYPFWNMTGGRNHI LTSVNDRGCCDIYRLGPDVQRPIKLVHFAQSGKVALRGRRAAAAAGVNESMLLDGQQLGWFIKERLWEDPALLAALIEYQHLNASGRPRFRGFPRYQWEA LWAEKEPCYRPEHDVAFPNYLPATEHGSWTKSLQDAYIYADPATYGGAVTHNSSRPRPVLFSFDGFSKPDMAYSGGVRQGLLALFGNTTRPDVSINKGGG PSLMLRSRFCFTPMGFGWGVRLTQAAMTGCVPVMVQDHVWPTLWDVLPYEKFSIRVSRHNLYRLFEILDSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 697 Download |
| MVMLRRTFVA LVCWAWASHT HSSALPAFRT IAKPCPEGCT RAGNCNAETG LCECPFGWTG 60 PVCEVPVLPA CRISASQDAS SGPPMVGSVF PKNCQCLKQL QNISCLESRY VYDYYLCEHG 120 AFWSWKSMHC FEYSNRPLDQ QLSGIPEPDA AGVVWKKGEW LSVVEGQDPF SFGNVSEPPK 180 TAMNSKQFFP LSRCPDRCNE RGNCFAWGAG HPPQCDCAAF YSGKACETVE AAHCPLGCSG 240 RGACKGGFCH CQPGWWGLGC SRSKAYEADE YAPHPTRLKI YVYDLPESVV HMRSHSDEWP 300 LHFPIYLAEH EFFNRLLGDW ATRTENPWEA NLFYIPTFTY YYIGNVGQPG KLFSRVVSYV 360 RHNYPFWNMT GGRNHILTSV NDRGCCDIYR LGPDVQRPIK LVHFAQSGKV ALRGRRAAAA 420 AGVNESMLLD GQQLGWFIKE RLWEDPALLA ALIEYQHLNA SGRPRFRGFP RYQWEALWAE 480 KEPCYRPEHD VAFPNYLPAT EHGSWTKSLQ DAYIYADPAT YGGAVTHNSS RPRPVLFSFD 540 GFSKPDMAYS GGVRQGLLAL FGNTTRPDVS INKGGGPSLM LRSRFCFTPM GFGWGVRLTQ 600 AAMTGCVPVM VQDHVWPTLW DVLPYEKFSI RVSRHNLYRL FEILDSITAE ELASLQAGLA 660 HWHRAFVWQP EFGGLAYNYT LESLQRRLSN MWTAMF* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-15 | 457 | 647 | 209 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 9.0e-18 | 274 | 408 | 137 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693329.1 | 0 | 54 | 405 | 2 | 368 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694919.1 | 0 | 30 | 696 | 8 | 674 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 22 | 696 | 17 | 680 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 8 | 692 | 21 | 700 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699926.1 | 0 | 28 | 696 | 167 | 782 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
