| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | g9878.t1 |
| Family | GT47 |
| Protein Properties | Length: 790 Molecular Weight: 85148.2 Isoelectric Point: 7.5737 |
| Chromosome | Chromosome/Scaffold: 9 Start: 4974095 End: 4982590 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 151 | 445 | 8.6e-32 |
| RRPHVYVYDIPHNLSSWHHPKNMDRGLHWLFWQRLLASGAMTADGDTADWYYIPVKMRSTSDGGRLMEAIEYVRRHWPWYDRLQGQRHFVIHTGDLGRGE VTRSVREATPNLTWLHHWGLTADAPHSGWRAAHRPGKDIVLPIHMGSRYSSRAAGLHPLAPQLPRSSGLLFVGRICGDRSQPDPARGWPHCATDRNDGYS QGVRQQVHYHHHHRPGFKVTASDPHYGLDLLRYRWCLAPSGGGHGNRQTVVTLAGCLPVVVSDDVLQPFEPEMDWGGFGLRAAHSDIPRLHELLA | |||
| Full Sequence |
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| Protein Sequence Length: 790 Download |
| MSIGLAVSRL LFAAWLAAFL QIRCIHARCS AECYKHATCN EAIDGGRCDC PKQLAGPDCS 60 LESAARVSPH EPCLNNCTGR GVCAWGECVC RRGNFGSDCS LSVAADDVDG GSSRSSRGRD 120 SGGSSRGQQQ QQPLKLQLLA GGNTPYVPRR RRPHVYVYDI PHNLSSWHHP KNMDRGLHWL 180 FWQRLLASGA MTADGDTADW YYIPVKMRST SDGGRLMEAI EYVRRHWPWY DRLQGQRHFV 240 IHTGDLGRGE VTRSVREATP NLTWLHHWGL TADAPHSGWR AAHRPGKDIV LPIHMGSRYS 300 SRAAGLHPLA PQLPRSSGLL FVGRICGDRS QPDPARGWPH CATDRNDGYS QGVRQQVHYH 360 HHHRPGFKVT ASDPHYGLDL LRYRWCLAPS GGGHGNRQTV VTLAGCLPVV VSDDVLQPFE 420 PEMDWGGFGL RAAHSDIPRL HELLAEAEQE DGGAGLRARA DSLPCAAQHL FWSGVSGAFM 480 QEDGRWDAFE FTLEILRMQQ TYPDLDPAQY AARDEQFRAF LYCGEADAPN GRYGMAAYGR 540 KWRAAWQERY GAASAAVGES LGIPTDADDE EGWKALYDRG GLEALKQTYG DGAVAAAVRQ 600 VADDEPRRRE GREGGSKGRG SERAHGEEDE EDGGGRGRRR LNSSSSSGSH SSGSSSSSGG 660 HSNGSSSSSG EGRPLWTRWG SLLRAALLGR GGGATGDEEA FRGAGGAGGG GAGRRRRGMS 720 TSVRRLTAAG GGGESEGGGG GQQHSLPLCS ISVWDAEEDR CAGGAPGGAA CAWHPAREAD 780 LGGCPRAWP* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-19 | 179 | 446 | 281 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001690974.1 | 0 | 261 | 520 | 26 | 281 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694808.1 | 0 | 47 | 322 | 336 | 613 | flagellar associated protein [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694808.1 | 0 | 385 | 736 | 617 | 939 | flagellar associated protein [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 16 | 523 | 60 | 553 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 47 | 523 | 9 | 471 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
