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Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a000151m |
Family | GT24 |
Protein Properties | Length: 1601 Molecular Weight: 180474 Isoelectric Point: 5.4219 |
Chromosome | Chromosome/Scaffold: 44 Start: 612320 End: 624502 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1294 | 1541 | 0 |
INIFSVASGHLYERFLKIMILSVLKNTHRPVKFWFIKNYLSPQFKDVIPHMAHEYGFEYELITYKWPTWLHKQKEKQRIIWAYKILFLDVIFPLALEKVI FVDADQIVRTDMGELYDMDLKGRPLAYTPFCDNNKDMDGYRFWKQGFWKDHLRGRPYHISALYVVDLVKFRETAAGDQLRVFYETLSKDPNSLSNLDQDL PNYAQHMVPIFSLPQEWLWCESWCGNATKSKAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1601 Download |
MGRSGFCFLI LIVFCICLSG HSVSAQNRSK PKNVQVALRA KWSGTPLLLE AGELLSKEWK 60 DFFWDFIESW LHSDNLDTES STAKDCLKKI AKFGKSLLTE PLASIFEFSL TLRSASPRLV 120 LYRQLAEESL SSFPLTDDVA PKTIEQNETA KTLTSESFLS GSNLKSPGNK CCWVDTGGSL 180 FFEVVDLLTW LDTPNDVTDG AFQQPEIFEF DHVHPDSTAG SPTAILYGAL GTECFKEFHK 240 VLSEAAKKGR AKYVVRSVLP SGCESKTTSC GAIGTKEPPN LGGYGVELAL KNMEYKAMDD 300 STVKKGVTLE DPHTEDLSQE VRGFIFSRIL ERKPELTSEV MAFRDYLLSA TVSDTLDVWE 360 LKDLGHQTAQ RIVHASDPLQ SMQEINQNFP SIVSSLSRTK LNDSIKDEII ENQRMIPPGK 420 SLLALNGALI NVEDIDLHSL VDMVHLELSL ADQYRKLQIP PSGVRKFLSV LPPSESYAFR 480 VDFRSPHVHY INNLEEDAMY KRWRSNINEA IDTIISLFEN NLPMRFGVIL YSENLIEKIE 540 ENDGELPVAH LKDDQDDISS LVMRLFLHIK ENHGALMAFQ FLSNVNKLRV ESAAEDSLEM 600 HQVEGAFVET ILPTATSPPQ ETLLKLEKDQ TLSELSHESS VFAFKLGLAK MGCSLLMNGL 660 VYEPNEEALI NAMNDELPRI QEQVYYGQIN SHTDVLDKFL SESGVQRYNA KIIADGKVKP 720 KFVSLCASIL AKESILNDLY YLHSLETMDD LKPVTHLVVV DMTSKKGMKL LREGIRYLIS 780 GSKIARVGVL FNANKDATLP SLVFMKAFEL TASSYSHKKG VLQFLDQLCS FYEQEYILAS 840 GDTKSYQKII DKVFQLADAN GLPSNAYESS LSGFSAENLR SYLNKVAQFL FRTIGVESGA 900 SAVVTNGRVI QLLEGSTFLS HDLHLLESLE FKQRIKHIAE IIEEIKWDDV DPDVLTSKFI 960 SDVVMAISSS SSTRDRSSES ARFEILSAEY SAVIMQNEHA SIHIDAVIDP LSSSGQKLSA 1020 LLRFLSKYVQ PSMRLVLNPV SSLADLPLKN YYRYVVPTTD DFSGTDHTVN GPTAFFSNMP 1080 LSKTLTMNLD VPEPWLVQPL VAIHDLDNIL LENLAETRTL QAVFELEALV LTGHCSEKDH 1140 EPPRGLQLIL GTRNTPHLVD TLVMANLGYW QMKVFPGLWY LQLAPGRSNE LYVMREDGEG 1200 GQDSTLSKQI TIDDLRGKLV HMEVKKRKGM EREKLLVPVD DDDSHSTTKK GSQNGWNSNI 1260 LKWASGFIGG KDQSKKEPNS SLEPRSGGRY GKTINIFSVA SGHLYERFLK IMILSVLKNT 1320 HRPVKFWFIK NYLSPQFKDV IPHMAHEYGF EYELITYKWP TWLHKQKEKQ RIIWAYKILF 1380 LDVIFPLALE KVIFVDADQI VRTDMGELYD MDLKGRPLAY TPFCDNNKDM DGYRFWKQGF 1440 WKDHLRGRPY HISALYVVDL VKFRETAAGD QLRVFYETLS KDPNSLSNLD QDLPNYAQHM 1500 VPIFSLPQEW LWCESWCGNA TKSKAKTIDL CNNPMTKEPK LQGAKRIVTE WPDLDLEARR 1560 FTAKILGENI EEPQEQIAPP HQIESTNEDS SEDNESKAEL * 1620 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01501 | Glyco_transf_8 | 7.0e-5 | 1298 | 1493 | 204 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd04194 | GT8_A4GalT_like | 4.0e-15 | 1294 | 1510 | 226 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 1.0e-57 | 1294 | 1541 | 258 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 3.0e-69 | 983 | 1166 | 188 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 8.0e-177 | 1294 | 1541 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG51883.1 | 0 | 8 | 1600 | 10 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
DDBJ | BAD28382.1 | 0 | 30 | 1595 | 36 | 1625 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
RefSeq | NP_177278.3 | 0 | 8 | 1600 | 10 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002268972.1 | 0 | 3 | 1600 | 6 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002529534.1 | 0 | 3 | 1491 | 6 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |