| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a000971m |
| Family | GT41 |
| Protein Properties | Length: 928 Molecular Weight: 103473 Isoelectric Point: 6.51 |
| Chromosome | Chromosome/Scaffold: 206 Start: 391767 End: 399210 |
| Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT41 | 362 | 867 | 0 |
| PNFSQSLNNLGVVYTVQGKMDAAASMIEKAIVANPTYAEAYNNLGVLYRDAGSISLAVEAYEQCLKIDPDSRNAGQNRLLAMNYINDGSDDKLYEVHRDW GRRFMRLFPQYTSWENIKDPERPLVIGYVSPDYFTHSVSYFIEAPLIYHDYANYKVVVYSAVVKADAKTSRFRDRVLKHGGAWRDIYGIDEKKVASMVRE DKIDILVELTGHTANNKLGMMACRPAPVQVTWIGYPNTTGLPTIDYRISDALADPVDTMQKHVEELVRLPNSFLCYTPSPEAGPVAPTPALSNGFVTFGS FNNLAKITPKVLQVWARILSAVPNSRLIVKCKPFCCDSVRQQFLTTLEKLGLESLRVDLLPLILLNHDHMQAYSLMDISLDTFPYAGTTTTCESLYMGVP CVTMGGSVHAHNVGVSLLKTVGLNNLVATNEDEYVDLAVKLASDVTALSNLRMRLRNLMSKSPLCDGSKFIRGLESAYRKMWRRYCKDDVPSLKQMELAQ VPPQQQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 928 Download |
| MELTKKEVDN EKVLVDGHVF LKEAQPSSAS RSPLGASAMK KSFEGKDALS YANILRSRNK 60 FVDAFAVYER VLEKDGENVE AYIGKGICLQ MQNLGRLAYE SFAEAVRLDP QNACALTHCG 120 ILYKDEGRLV EAAEMYQKAL KADPLYKLAA ECLAIVLTDL GTSLKLAGNT QEGIQKYYEA 180 IKIDPHYAPA YYNLGVVYSE MMQYETALNC YEKAAIERPM YAEAYCNMGV IYKNRGDLES 240 AIACYERCLT VSPNFEIAKN NMAIALTDLG TKVKLEGDIN QGVAYYKKAL YYNWHYADAM 300 YNLGVAYGEM LMFDMAIVFY ELAFHFNPHC AEACNNLGVI YKDRDNLDKA VECYQLALSI 360 KPNFSQSLNN LGVVYTVQGK MDAAASMIEK AIVANPTYAE AYNNLGVLYR DAGSISLAVE 420 AYEQCLKIDP DSRNAGQNRL LAMNYINDGS DDKLYEVHRD WGRRFMRLFP QYTSWENIKD 480 PERPLVIGYV SPDYFTHSVS YFIEAPLIYH DYANYKVVVY SAVVKADAKT SRFRDRVLKH 540 GGAWRDIYGI DEKKVASMVR EDKIDILVEL TGHTANNKLG MMACRPAPVQ VTWIGYPNTT 600 GLPTIDYRIS DALADPVDTM QKHVEELVRL PNSFLCYTPS PEAGPVAPTP ALSNGFVTFG 660 SFNNLAKITP KVLQVWARIL SAVPNSRLIV KCKPFCCDSV RQQFLTTLEK LGLESLRVDL 720 LPLILLNHDH MQAYSLMDIS LDTFPYAGTT TTCESLYMGV PCVTMGGSVH AHNVGVSLLK 780 TVGLNNLVAT NEDEYVDLAV KLASDVTALS NLRMRLRNLM SKSPLCDGSK FIRGLESAYR 840 KMWRRYCKDD VPSLKQMELA QVPPQQQQVV PEEIAVRITE PKKVVSTFAA PIKANGFYLG 900 QCSSAKTSNA EENGSLLNQS RNSGKLS* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam13844 | Glyco_transf_41 | 5.0e-17 | 485 | 634 | 151 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| cd00189 | TPR | 8.0e-21 | 156 | 254 | 99 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| pfam13844 | Glyco_transf_41 | 1.0e-23 | 657 | 843 | 187 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| COG3914 | Spy | 6.0e-87 | 314 | 846 | 562 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005515 | protein binding |
| GO:0042802 | identical protein binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACF96937.1 | 0 | 15 | 927 | 17 | 934 | SPINDLY [Sinningia speciosa] |
| Swiss-Prot | O82039 | 0 | 1 | 927 | 1 | 932 | SPY_PETHY RecName: Full=Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY; AltName: Full=PhSPY |
| Swiss-Prot | Q8RVB2 | 0 | 1 | 927 | 1 | 931 | SPY_SOLLC RecName: Full=Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY; Short=LeSPY |
| RefSeq | XP_002281883.1 | 0 | 1 | 914 | 1 | 912 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002530535.1 | 0 | 1 | 927 | 1 | 930 | o-linked n-acetylglucosamine transferase, ogt, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1w3b_B | 6e-37 | 87 | 438 | 42 | 378 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 1e-32 | 107 | 438 | 27 | 344 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 1e-26 | 1 | 372 | 23 | 380 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 2e-18 | 53 | 310 | 143 | 386 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 0.00000000004 | 49 | 237 | 207 | 388 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
 | ||||
| Hit | Length | Start | End | EValue |
| DY295408 | 384 | 427 | 808 | 0 |
| GT041789 | 337 | 342 | 678 | 0 |
| GT041789 | 109 | 169 | 275 | 0.000000000009 |
| GT041789 | 125 | 233 | 355 | 0.000002 |
| GT041789 | 107 | 278 | 382 | 0.00004 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
