Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a003679m |
Family | GT47 |
Protein Properties | Length: 571 Molecular Weight: 65667.4 Isoelectric Point: 10.032 |
Chromosome | Chromosome/Scaffold: 79 Start: 1007764 End: 1010404 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 239 | 521 | 0 |
EKTLKIYVYAEGEKPVFHQPELSGIYASEGWFMKQLEENKHFITKNPQKAHLFYLPFSSHLLQQTLYVPNSHSRKNLVRYLSNYLKTITKKHPFWNRTDG ADHFLAACHDWAPAETSRIMKNCIRALCNADVSEGFHFSKDVSIPETYVRHPTNPLKDIGGKPPSQRKILAFFAGKLHGYLRPILLNHWENKDPDMKISG KLQGLKGNLTYIEYMKSSKYCISAKGYEAYTPRVVEAIFYECVPVIISDNFVPPFFETLNWESFAVFVMEKDIPNLKNILLAI |
Full Sequence |
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Protein Sequence Length: 571 Download |
METRRLLWLM ALLFSLVLLV QYIELPYGYV LSSFLSFTKS RSNSAKTNHA RDSSVNITSS 60 SDEHVVRNKS STPELAPVQH GYNVSIPKYI SSKNSSSVDL QLTNAAPTNT KKKDRNSQTT 120 IPQVANMVLN NEKPKKIAQS DLSASVNSSF VNGTSSKMRR RFKGPPSRVV PMSEMNHMLT 180 ESRLSFRSVK PRWPSEVDKE LLNARTQIES AQIVETSPHI DVSVYRNFSS FLRSYDLMEK 240 TLKIYVYAEG EKPVFHQPEL SGIYASEGWF MKQLEENKHF ITKNPQKAHL FYLPFSSHLL 300 QQTLYVPNSH SRKNLVRYLS NYLKTITKKH PFWNRTDGAD HFLAACHDWA PAETSRIMKN 360 CIRALCNADV SEGFHFSKDV SIPETYVRHP TNPLKDIGGK PPSQRKILAF FAGKLHGYLR 420 PILLNHWENK DPDMKISGKL QGLKGNLTYI EYMKSSKYCI SAKGYEAYTP RVVEAIFYEC 480 VPVIISDNFV PPFFETLNWE SFAVFVMEKD IPNLKNILLA IPKKRYVEMQ ERVRGVQKHF 540 LWHRSPVKYD VFHMILHSVW YNRVFQMTDG * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-68 | 238 | 521 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 109 | 567 | 139 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 85 | 567 | 194 | 666 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 108 | 567 | 16 | 468 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 175 | 567 | 1 | 395 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 165 | 566 | 51 | 452 | catalytic, putative [Ricinus communis] |