Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a003863m |
Family | GT68 |
Protein Properties | Length: 560 Molecular Weight: 63398.8 Isoelectric Point: 7.3186 |
Chromosome | Chromosome/Scaffold: 7 Start: 317180 End: 319817 |
Description | O-fucosyltransferase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT68 | 241 | 534 | 0 |
NRVLVIPSSKVDFPFHRVLDIETINKCLGRKVVVTFEEFAEIKKNHLHIDKFMCYFSLPQPCFMDDDHLKKLKGLGLSLGKIETVWKEDVKKPNQRKVDD VTAKFSSDDDVIAVGDVFFADVEREWVMQPGGPIAHKCKTLIEPSRLILLTAHRFIQTFLGKDFIALHFRRHGFLKFCNAKQPSCFFPVPQAAECINRVV ERANTPVVYLSTDAAASETGLLQSLVVWNGKTVPLVQRPARNLAEKWDALLYRHGLEGDSQVEAMLDKTICALSSVFIGSSGSTFTEDILRIRK |
Full Sequence |
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Protein Sequence Length: 560 Download |
MMERDSSDEE EDHENLISQN ARPNDVVKSP TNHTRRSALR IDGGGRLSGA ARGFNKRYLL 60 AILLPMVILI LYFTTDLKSL FQMRIPTIKD IGGNSPLNRM RESELRALYL LKQQELQLLK 120 MWNYTTLQNQ SNSSSVNNSN SFDEDLKSRV FSQISLNKQI QGILLSSHES EGFPDLNENN 180 TDASLSGWNM CGKVDQKLSE RRTIEWKPRS NKYLLAICVS GQMSNHLICL EKHMFFAALL 240 NRVLVIPSSK VDFPFHRVLD IETINKCLGR KVVVTFEEFA EIKKNHLHID KFMCYFSLPQ 300 PCFMDDDHLK KLKGLGLSLG KIETVWKEDV KKPNQRKVDD VTAKFSSDDD VIAVGDVFFA 360 DVEREWVMQP GGPIAHKCKT LIEPSRLILL TAHRFIQTFL GKDFIALHFR RHGFLKFCNA 420 KQPSCFFPVP QAAECINRVV ERANTPVVYL STDAAASETG LLQSLVVWNG KTVPLVQRPA 480 RNLAEKWDAL LYRHGLEGDS QVEAMLDKTI CALSSVFIGS SGSTFTEDIL RIRKDWGSAS 540 VCDEYLCQGE LPNFIAEDE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd11548 | NodZ_like | 0.004 | 339 | 527 | 192 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
pfam10250 | O-FucT | 0.003 | 236 | 526 | 321 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
cd11296 | O-FucT_like | 2.0e-5 | 213 | 261 | 49 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11298 | O-FucT-2 | 1.0e-7 | 400 | 535 | 138 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 1.0e-15 | 375 | 533 | 169 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAM66093.1 | 0 | 2 | 559 | 1 | 566 | unknown [Arabidopsis thaliana] |
RefSeq | NP_173170.2 | 0 | 2 | 559 | 1 | 564 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_199853.1 | 0 | 2 | 559 | 1 | 566 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002264087.1 | 0 | 2 | 559 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303337.1 | 0 | 2 | 559 | 1 | 527 | predicted protein [Populus trichocarpa] |