| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a003898m |
| Family | AA3 |
| Protein Properties | Length: 557 Molecular Weight: 61331.9 Isoelectric Point: 8.9257 |
| Chromosome | Chromosome/Scaffold: 51 Start: 535997 End: 538473 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA3 | 47 | 553 | 0 |
| SEYFDYIIVGGGTAGCALAATLSASAKVLLLERGGLPYGDPNLGHVTGFRKTLADTSTTSPSQLFVSTDGVFNHRGRVLGGSSAINAGFYTRASNQYVVE AGWDPRLVNESYGWVETKVVFRPRVLEWQSAVRDGLLEAGVSPLRGTTYEHLHGTKTGGSTFDEHGYRHTAADLLEYADPAKITVYLYATVYKILFGSSP ERRTKSYGVLFRDSKGNRHVAYLNSGPTNEVILSAGALGSPQLLMLNGIGPARQLRAHGITVILDQPMVGQGMSDNPMNAVIIPSHRPVEVSLIQVVGIT NAGSYIEAASRVLEQALTPALVQHFTRLANQTFPEGTRNIQDVIILEKVMGPFSRGYLELQSNDPNDNPRVTFNYFQDPRDLQRCVQGMGIVKRVIESRP VSAFRYPFSTFQSLINLMLAIPNNLRRRHVSASHSMEQFCVDTVMTIWHYHGGCQVDRVVDRDYRVIGVDGLRVIDGSTFYTSPGTNPQATVMMLGRYMG QKILRER | |||
| Full Sequence |
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| Protein Sequence Length: 557 Download |
| MASVITYRWS PLLAVSLWIF FFIIIACYAE KAPYSSFARD ATSAPPSEYF DYIIVGGGTA 60 GCALAATLSA SAKVLLLERG GLPYGDPNLG HVTGFRKTLA DTSTTSPSQL FVSTDGVFNH 120 RGRVLGGSSA INAGFYTRAS NQYVVEAGWD PRLVNESYGW VETKVVFRPR VLEWQSAVRD 180 GLLEAGVSPL RGTTYEHLHG TKTGGSTFDE HGYRHTAADL LEYADPAKIT VYLYATVYKI 240 LFGSSPERRT KSYGVLFRDS KGNRHVAYLN SGPTNEVILS AGALGSPQLL MLNGIGPARQ 300 LRAHGITVIL DQPMVGQGMS DNPMNAVIIP SHRPVEVSLI QVVGITNAGS YIEAASRVLE 360 QALTPALVQH FTRLANQTFP EGTRNIQDVI ILEKVMGPFS RGYLELQSND PNDNPRVTFN 420 YFQDPRDLQR CVQGMGIVKR VIESRPVSAF RYPFSTFQSL INLMLAIPNN LRRRHVSASH 480 SMEQFCVDTV MTIWHYHGGC QVDRVVDRDY RVIGVDGLRV IDGSTFYTSP GTNPQATVMM 540 LGRYMGQKIL RERIPQ* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01810 | betA | 4.0e-18 | 121 | 550 | 484 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| pfam05199 | GMC_oxred_C | 4.0e-21 | 398 | 542 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR03970 | Rv0697 | 5.0e-29 | 121 | 542 | 444 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| COG2303 | BetA | 2.0e-30 | 121 | 556 | 490 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 34 | 554 | 546 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI31862.1 | 0 | 9 | 553 | 6 | 537 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI34759.1 | 0 | 27 | 554 | 24 | 572 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002267807.1 | 0 | 9 | 553 | 6 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 9 | 556 | 5 | 572 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510860.1 | 0 | 9 | 554 | 6 | 571 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3red_L | 0 | 34 | 553 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_K | 0 | 34 | 553 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_J | 0 | 34 | 553 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_I | 0 | 34 | 553 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_H | 0 | 34 | 553 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
