Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a003962m |
Family | AA3 |
Protein Properties | Length: 553 Molecular Weight: 60262.5 Isoelectric Point: 8.9707 |
Chromosome | Chromosome/Scaffold: 1 Start: 552849 End: 554876 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 48 | 550 | 0 |
EDYYDYIVVGGGTAGCPLAATLSEKFRVLVLERGGVPFGDPNLMNRDGFLTALTEVDAYESPAQAFTSEDGVPNARGRVLGGSSAINAGFYSRADPDFYA RSGINWDLPTVNQSYKWVENAVVFRPDLNNWQSAVRDALLEAGIYPYNGFTLDHIVGTKIGGSTFDNSGHRHTAADLLGYSNPSNIKIVIHATVERILLA SKNSNPRTQSEAIGVVFRDRTGQYHHAMVRDGGEILLCAGALGTPQLLLLSGIGPRPYLASWGIPVAHHSPYVGQFLYDNPRNGISIVPPVPLDHSLIQV VGITSSGTYLEAASNIVPFTSPARPAFIRSRSPGGSSTFITVATLMEKIVGPASHGSLRLASTDARANPRVRFNYFSNPSDLDLCVNGTRRIGHVLRSRA MEDFRFHQWFGGREFRYVGPPLPRDLSSDARLREFCRRTVTTIWHYHGGCLVGRVVDGDLKVIGIDSLRVIDGSVFTVSPGTNPQATLLMMGRYFGLKLL KER |
Full Sequence |
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Protein Sequence Length: 553 Download |
MGGKFFTLWP PFLILLILSS IGSLRTTYSQ PSPAYMGFLS NATEFPAEDY YDYIVVGGGT 60 AGCPLAATLS EKFRVLVLER GGVPFGDPNL MNRDGFLTAL TEVDAYESPA QAFTSEDGVP 120 NARGRVLGGS SAINAGFYSR ADPDFYARSG INWDLPTVNQ SYKWVENAVV FRPDLNNWQS 180 AVRDALLEAG IYPYNGFTLD HIVGTKIGGS TFDNSGHRHT AADLLGYSNP SNIKIVIHAT 240 VERILLASKN SNPRTQSEAI GVVFRDRTGQ YHHAMVRDGG EILLCAGALG TPQLLLLSGI 300 GPRPYLASWG IPVAHHSPYV GQFLYDNPRN GISIVPPVPL DHSLIQVVGI TSSGTYLEAA 360 SNIVPFTSPA RPAFIRSRSP GGSSTFITVA TLMEKIVGPA SHGSLRLAST DARANPRVRF 420 NYFSNPSDLD LCVNGTRRIG HVLRSRAMED FRFHQWFGGR EFRYVGPPLP RDLSSDARLR 480 EFCRRTVTTI WHYHGGCLVG RVVDGDLKVI GIDSLRVIDG SVFTVSPGTN PQATLLMMGR 540 YFGLKLLKER AR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR03970 | Rv0697 | 1.0e-39 | 52 | 539 | 535 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 2.0e-43 | 52 | 539 | 556 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 1.0e-47 | 51 | 552 | 561 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PRK02106 | PRK02106 | 7.0e-57 | 51 | 539 | 570 | + choline dehydrogenase; Validated | ||
PLN02785 | PLN02785 | 0 | 29 | 550 | 572 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABE65766.1 | 0 | 33 | 552 | 36 | 552 | mandelonitrile lyase [Arabidopsis thaliana] |
GenBank | ACN31582.1 | 0 | 34 | 550 | 36 | 582 | unknown [Zea mays] |
RefSeq | NP_177448.1 | 0 | 33 | 552 | 36 | 552 | (R)-mandelonitrile lyase, putative / (R)-oxynitrilase, putative [Arabidopsis thaliana] |
RefSeq | XP_002277531.1 | 0 | 10 | 552 | 9 | 548 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311915.1 | 0 | 33 | 550 | 2 | 517 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 34 | 551 | 10 | 518 | A Chain A, Crystal Structure Of The Polygalacturonase From Colletotrichum Lupini And Its Implications For The Interaction With Polygalacturonase- Inhibiting Proteins |
PDB | 3gdp_A | 0 | 34 | 551 | 10 | 518 | A Chain A, Crystal Structure Of The Polygalacturonase From Colletotrichum Lupini And Its Implications For The Interaction With Polygalacturonase- Inhibiting Proteins |
PDB | 3gdn_B | 0 | 34 | 551 | 10 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 34 | 551 | 10 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 34 | 551 | 10 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |