y
Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a004154m |
Family | GT47 |
Protein Properties | Length: 542 Molecular Weight: 61474.5 Isoelectric Point: 9.1522 |
Chromosome | Chromosome/Scaffold: 13 Start: 157666 End: 160557 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 206 | 488 | 0 |
EKNFKVFVYEEGEHPIFHNGPCGSIYSMEGNFIYKLEISKFRTRDPEKAHVFFLPFSVTSIVHFIFDKNSRDHWLPMKQTVSDYVELVAAKYPYWNRSLG SDHFMLSCHDWGPELSKSLPELFNNSIRALCNANTTEGFKPSKDVSIPEINLPGGRTNGLIGGPSPSRRPVLVFFAGGLHGPIRPALLEHWENSKDKDVQ IHQYLPKNVSYSALMRKSKYCVCPSGYEVASPRMVEALYTGCVPVLVKDHYVPPFSDVLNWKSFAVEIPVGDIPNLRNILLGI |
Full Sequence |
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Protein Sequence Length: 542 Download |
MEGCRKSVCS WWKTASSSTR LLGFMLPLMV VSVMVVLMGY NSSNWFFDSG FYPWAWGSVY 60 PPRAPFSQGF VPPPADGGID AFQWRQTVVG GGGEREEALV VDYNLHRSAA PPLSIQVSAA 120 EPPVTKKNDD LMNATNKSSD SRVLPLSPGI NRRFSNLQIL EAKMQQSRTA IRDARKESVI 180 HDPDYVPSGP IYWNPSAFHR SYLEMEKNFK VFVYEEGEHP IFHNGPCGSI YSMEGNFIYK 240 LEISKFRTRD PEKAHVFFLP FSVTSIVHFI FDKNSRDHWL PMKQTVSDYV ELVAAKYPYW 300 NRSLGSDHFM LSCHDWGPEL SKSLPELFNN SIRALCNANT TEGFKPSKDV SIPEINLPGG 360 RTNGLIGGPS PSRRPVLVFF AGGLHGPIRP ALLEHWENSK DKDVQIHQYL PKNVSYSALM 420 RKSKYCVCPS GYEVASPRMV EALYTGCVPV LVKDHYVPPF SDVLNWKSFA VEIPVGDIPN 480 LRNILLGIST RQYIRMQRRG VTVRRHFEVN LTPKRYDVFH MILHSIWLRR LNVRLHGVED 540 L* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-68 | 205 | 488 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 131 | 538 | 1 | 408 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 130 | 538 | 110 | 518 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 205 | 536 | 1 | 331 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002326234.1 | 0 | 205 | 533 | 1 | 328 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528630.1 | 0 | 182 | 536 | 213 | 566 | catalytic, putative [Ricinus communis] |