| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a005268m |
| Family | GH29 |
| Protein Properties | Length: 492 Molecular Weight: 55473.1 Isoelectric Point: 8.7718 |
| Chromosome | Chromosome/Scaffold: 51 Start: 441168 End: 443783 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 49 | 346 | 0 |
| QLKWQQREIIMFLHFGVNTFTDSEWGTGLESPSVFYPTGLDPTQWAHTAARAGISLMILTAKHHDGFCLWPSKYTDHSVVRSPWNNGNGDVVREFVDAAK AHGIDAGLYLSPWDRHDTRYGHVELYNEYYLAQLQELLTRYGGVREIWFDGAKGANATNMTYYFNDWFSMVKELQSTINIFSDAGPDIRWVGNEKGYAGS TCWSTINATSLSIGNATILDYLNTGDPKGTNWLPAECDVSIRPGWFWHKSQAPKKLSELLEIYYKSVGRNCLLLLNVPPNTTGLISESDVQRLSQLRR | |||
| Full Sequence |
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| Protein Sequence Length: 492 Download |
| MAEKSYNYLH IFTLLMLLSP LANSLKNHDR LKLATPPPLP ILPLPSFSQL KWQQREIIMF 60 LHFGVNTFTD SEWGTGLESP SVFYPTGLDP TQWAHTAARA GISLMILTAK HHDGFCLWPS 120 KYTDHSVVRS PWNNGNGDVV REFVDAAKAH GIDAGLYLSP WDRHDTRYGH VELYNEYYLA 180 QLQELLTRYG GVREIWFDGA KGANATNMTY YFNDWFSMVK ELQSTINIFS DAGPDIRWVG 240 NEKGYAGSTC WSTINATSLS IGNATILDYL NTGDPKGTNW LPAECDVSIR PGWFWHKSQA 300 PKKLSELLEI YYKSVGRNCL LLLNVPPNTT GLISESDVQR LSQLRRAIDT IFTSNSAVKC 360 SVEASSPRGG ENGNFGPENV LDEDHLWTYW APSENEKKDY WIEFRAKSSG IKFNVIRIQE 420 AIGLGQRIKK HEIYVDGIRV AKGSTVGYKR LHRLKMGVVH GNSVRIKIVK AKGIPLISSV 480 GFYFDPFWKP K* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00812 | Alpha_L_fucos | 8.0e-30 | 59 | 344 | 332 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 1.0e-30 | 83 | 344 | 280 | + Alpha-L-fucosidase. | ||
| COG3669 | COG3669 | 2.0e-62 | 49 | 483 | 449 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 48 | 490 | 22 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 32 | 490 | 3 | 461 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 49 | 490 | 41 | 482 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 8 | 490 | 7 | 483 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 46 | 490 | 40 | 483 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 40 | 483 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 40 | 483 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3mo4_B | 0 | 45 | 478 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 45 | 478 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 45 | 478 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
