Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a005291m |
Family | GT47 |
Protein Properties | Length: 491 Molecular Weight: 56153.2 Isoelectric Point: 8.7762 |
Chromosome | Chromosome/Scaffold: 55 Start: 627183 End: 630287 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 111 | 429 | 0 |
LLRVYMYDLPAEFHFGLLGWKGDGNRTWPDLNDRDKLPSYPGGLNLQHSIEYWLTLDLLASNNPNVTRGCSAIRVKNSSEADVVFVPFFSSLSYNRYSKP EGKQKISLDRILQEKLVEFLKNRREWKRKGGGDHLVVAHHPNSMLFARRKLGSAMFVLADFGRYPTEVANVEKDVIAPYRHMVRAIAADDSPPFEERPTL VYFQGAIYRKDGGEIRQELYYLLKDEKDAHFAFGSVQSNGVRQAGKGMSSSKFCLNIAGDTPSSNRLFDAIATHCVPVVISDEIELPFEDILDYSEFCVF VKSSDAVKKGYLVNLLRSI |
Full Sequence |
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Protein Sequence Length: 491 Download |
MILKMPSSVS EKRIFPSKLL SLLIAFSILL LISSSLSLLH FDEDSSVPKS VLQFIVVNNS 60 SIHSKPNLKT GDPQTIPLKR PVFEIEKRVV EEQEQENYTR DKSCDQENKD LLRVYMYDLP 120 AEFHFGLLGW KGDGNRTWPD LNDRDKLPSY PGGLNLQHSI EYWLTLDLLA SNNPNVTRGC 180 SAIRVKNSSE ADVVFVPFFS SLSYNRYSKP EGKQKISLDR ILQEKLVEFL KNRREWKRKG 240 GGDHLVVAHH PNSMLFARRK LGSAMFVLAD FGRYPTEVAN VEKDVIAPYR HMVRAIAADD 300 SPPFEERPTL VYFQGAIYRK DGGEIRQELY YLLKDEKDAH FAFGSVQSNG VRQAGKGMSS 360 SKFCLNIAGD TPSSNRLFDA IATHCVPVVI SDEIELPFED ILDYSEFCVF VKSSDAVKKG 420 YLVNLLRSIE RDQWTKMWER LKEISGHFEY NYPSKSGDAV DMIWQTVYRK RSPTMLSVHR 480 KNRYSRLQVL * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-55 | 112 | 429 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_565089.1 | 0 | 9 | 490 | 4 | 455 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 9 | 490 | 1 | 451 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 100 | 490 | 23 | 412 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 112 | 486 | 3 | 374 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 45 | 489 | 37 | 489 | catalytic, putative [Ricinus communis] |