Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a005355m |
Family | GT47 |
Protein Properties | Length: 488 Molecular Weight: 55425.4 Isoelectric Point: 8.403 |
Chromosome | Chromosome/Scaffold: 13 Start: 151444 End: 154576 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 154 | 434 | 0 |
KLFKIYVYEDGDPPLFHYSKSKGILGIEGILIHQIEISKFRTRDPGKAHVYFIPLSVQSIATYAYVIHNRAWSPLQNIARDYVKLISTKYPHWNQTLGRD HFILGCHDWTPTISHGVPLLFKNSIRVLCNANTSEGFKPSIDVSMPEIYLPEGTMDGLIGGPPPSDRSILVFYAGGVHGPIRQMLMDQWKDNKDPEVQIH EYLPKNMSYYDVFRRSKYCICPSGWEVASPRMVEALYMGCVPVLLKESYAKPFDDVLDWSTFAVDVRVDEIRDLKKILMGI |
Full Sequence |
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Protein Sequence Length: 488 Download |
MADSSSSSSP SSSSSSSKLV YFVIFPLILL SGLVIILNQK PSTSYNSFPY FHYPAAAATA 60 ASRASGAVTA APAKQDHVPV KPRFTKNGSK RDKSPSDYNL DNLDMVEASL AKARETMHQA 120 RLNNETSFDP DYVPEGSIYR NANAFHRSYL EMEKLFKIYV YEDGDPPLFH YSKSKGILGI 180 EGILIHQIEI SKFRTRDPGK AHVYFIPLSV QSIATYAYVI HNRAWSPLQN IARDYVKLIS 240 TKYPHWNQTL GRDHFILGCH DWTPTISHGV PLLFKNSIRV LCNANTSEGF KPSIDVSMPE 300 IYLPEGTMDG LIGGPPPSDR SILVFYAGGV HGPIRQMLMD QWKDNKDPEV QIHEYLPKNM 360 SYYDVFRRSK YCICPSGWEV ASPRMVEALY MGCVPVLLKE SYAKPFDDVL DWSTFAVDVR 420 VDEIRDLKKI LMGISTEKYV EMQREGIRVR RHFEVNFPPK RYDVFHMVLH SIWLRRINVQ 480 LHDAHET* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-57 | 152 | 434 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 100 | 484 | 25 | 408 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 100 | 484 | 135 | 518 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 152 | 482 | 1 | 331 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002524591.1 | 0 | 103 | 483 | 121 | 504 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002528630.1 | 0 | 124 | 483 | 209 | 567 | catalytic, putative [Ricinus communis] |