| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a005660m |
| Family | GT47 |
| Protein Properties | Length: 476 Molecular Weight: 54534.7 Isoelectric Point: 9.3176 |
| Chromosome | Chromosome/Scaffold: 85 Start: 958185 End: 960772 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 83 | 399 | 0 |
| KKVKIYMYDLPRRFTYGVIESYAEARGGETVGNDALLKYPGNQHSAEWYLFSDLNRPGDQRIDSALTRVMDPEEADLFYVPFFSSLSLVANPIRSATVNV SPNRTVYNDEQTQEALMEWLEEQVYWKRNNGWDHVFICQDPNALYKIIDRAKNGVLLVSDFGRLGANQASLVKDVILPYSHRINSYKGEIGLENRKSLLF FMGNRYRKEGGKIRDMLFQVLENEQEVIIKHGAQSRESRRMASQGMHTSKFCLHPAGDTPSACRLFDAIVSLCVPVIVSDYIELPFEDAIDYRKIAIFLD TYTAVKPGSLVKLLRKV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 476 Download |
| MNLRPKLRSP LSIPSPPTSP LPYSSKSVLT KMPRKSLLRP TLVLAFLSLF ALYSFFFYNP 60 PNYNTNTSIN LDNRSFRSVD DNKKVKIYMY DLPRRFTYGV IESYAEARGG ETVGNDALLK 120 YPGNQHSAEW YLFSDLNRPG DQRIDSALTR VMDPEEADLF YVPFFSSLSL VANPIRSATV 180 NVSPNRTVYN DEQTQEALME WLEEQVYWKR NNGWDHVFIC QDPNALYKII DRAKNGVLLV 240 SDFGRLGANQ ASLVKDVILP YSHRINSYKG EIGLENRKSL LFFMGNRYRK EGGKIRDMLF 300 QVLENEQEVI IKHGAQSRES RRMASQGMHT SKFCLHPAGD TPSACRLFDA IVSLCVPVIV 360 SDYIELPFED AIDYRKIAIF LDTYTAVKPG SLVKLLRKVT PERILEFQKE LKKVKRYFEY 420 EEANGTVKEI WRQVSLKLPL IKLMSNRDKR IVLRDLTQPD CSCLCSNQSG VHTTL* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-71 | 82 | 399 | 329 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN68074.1 | 0 | 32 | 475 | 1 | 461 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002276440.1 | 0 | 1 | 475 | 3 | 494 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318294.1 | 0 | 89 | 475 | 1 | 382 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322391.1 | 0 | 32 | 475 | 1 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523645.1 | 0 | 32 | 475 | 1 | 452 | catalytic, putative [Ricinus communis] |
