Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a005764m |
Family | GT47 |
Protein Properties | Length: 472 Molecular Weight: 53416.6 Isoelectric Point: 8.8037 |
Chromosome | Chromosome/Scaffold: 64 Start: 827801 End: 829621 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 45 | 395 | 0 |
HNSIRVYVSPLPRSLNYGLLEKYWALTSDTRVGSEVDNEIRITLLPKLSPKSLPYPENPIIKQYSAEYWILGDLLAPDELKRESFVKRVVDSKEADVVFV PFFATLSAELQLIINKSVFRKRVEENEDYTRQKMVVDLVKKSEAWRKSGGRDHVFVVTDPVAMWHVKDEIAPAVLLVVDFGGWYRLDSKTSNDSSSDLTI HHTQVSLLKDVIVPYTHLLPTLRISENKKRHTLLYFKGAKHRHRTGLVREKLWDLLVNEDGVIIEEGFPNATGKEQSIKGMRSSEFCLHPAGDTPTSCRL FDSIQSLCIPVIVSDSVELPFEGMVDYLEFSVFVSVSDAMKPDWLVSHLRS |
Full Sequence |
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Protein Sequence Length: 472 Download |
MAPKTPPLFL ILTLLSLLSL TFFYLHSTTT PPPPPTPTNA LTAAHNSIRV YVSPLPRSLN 60 YGLLEKYWAL TSDTRVGSEV DNEIRITLLP KLSPKSLPYP ENPIIKQYSA EYWILGDLLA 120 PDELKRESFV KRVVDSKEAD VVFVPFFATL SAELQLIINK SVFRKRVEEN EDYTRQKMVV 180 DLVKKSEAWR KSGGRDHVFV VTDPVAMWHV KDEIAPAVLL VVDFGGWYRL DSKTSNDSSS 240 DLTIHHTQVS LLKDVIVPYT HLLPTLRISE NKKRHTLLYF KGAKHRHRTG LVREKLWDLL 300 VNEDGVIIEE GFPNATGKEQ SIKGMRSSEF CLHPAGDTPT SCRLFDSIQS LCIPVIVSDS 360 VELPFEGMVD YLEFSVFVSV SDAMKPDWLV SHLRSYSDEQ KNKFRKNMAK VQQIFQYENG 420 HPGGIGPANL DGAVNYIWKK VYQKLPIIKE AVTRERRKPS GVSVPLRCHC T* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-58 | 103 | 396 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 35 | 470 | 44 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 9 | 471 | 22 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 6 | 471 | 16 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 18 | 471 | 1 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 35 | 471 | 42 | 478 | catalytic, putative [Ricinus communis] |