Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a005938m |
Family | GT47 |
Protein Properties | Length: 465 Molecular Weight: 53123.9 Isoelectric Point: 8.9691 |
Chromosome | Chromosome/Scaffold: 311 Start: 27063 End: 29082 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 71 | 388 | 0 |
ILKVFMYDLPPQFHFGLLGWKAAGPTVWPDIRSQQVPEYAGGLNLQHSIEYWLTLDLLNSEFSKNLSGRTAVRVRNSSEADVIFVPFFASISYNRYSKVK TRGSKKSINDLLQENLVSFLSAQEEWKKSGGKDHIVVAHHPNSLLYARMKLWPAIYILADFGRYPPTVANVEKDVIAPYKHLITSYVDDKSDFDSRKTLL HFQGSIYRKDGGIIRQELYYMLKNEKDVHFSFGSIQGDGISTASKGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPFEDIINYSEFCIFV PSSDAVRENFLINLIRNI |
Full Sequence |
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Protein Sequence Length: 465 Download |
MSKNKMWLIS HKFLFCLFLM TSTLLILSRL LTLRSTGGPY SLDSITFSSS NILTMAETEN 60 LDSSCYTNNQ ILKVFMYDLP PQFHFGLLGW KAAGPTVWPD IRSQQVPEYA GGLNLQHSIE 120 YWLTLDLLNS EFSKNLSGRT AVRVRNSSEA DVIFVPFFAS ISYNRYSKVK TRGSKKSIND 180 LLQENLVSFL SAQEEWKKSG GKDHIVVAHH PNSLLYARMK LWPAIYILAD FGRYPPTVAN 240 VEKDVIAPYK HLITSYVDDK SDFDSRKTLL HFQGSIYRKD GGIIRQELYY MLKNEKDVHF 300 SFGSIQGDGI STASKGMHSS KFCLNIAGDT PSSNRLFDAI ASHCVPVIIS DDIELPFEDI 360 INYSEFCIFV PSSDAVRENF LINLIRNISK EKWTRMWEKL KEVEHFFEFH YPSQENDAVQ 420 MIWRAILRKV PSIDRKIHKL GRFSRGVVSG ESGLRSISVP RNFW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-56 | 72 | 388 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 53 | 464 | 103 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
EMBL | CAN68950.1 | 0 | 34 | 464 | 37 | 488 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268382.1 | 0 | 34 | 464 | 37 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 2 | 444 | 8 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325457.1 | 0 | 60 | 464 | 59 | 463 | predicted protein [Populus trichocarpa] |