| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a006022m |
| Family | GT47 |
| Protein Properties | Length: 462 Molecular Weight: 52755.4 Isoelectric Point: 9.4639 |
| Chromosome | Chromosome/Scaffold: 98 Start: 1403 End: 4740 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 87 | 384 | 0 |
| SLRIYVYDEDEIEGLKLLLYGREGKISADACVKGQWGTQVKIHRLLLQSTFRTKKKEEADLFFVPSYVKCVRMMGGLSDKEINQTYVKVLSQMPYFRLSG GRNHVFVFPSGAGAHLFKSWATYLNRSIILTPEGDRTDKRDTTAFNTWKDIIIPGNVDDGMTAHKSRLVDPLPLSRRKYLANYLGRAQGKAGRLQLIDLA KQYPDKLESPELKFSGPEKLGRTEYFQHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDQAELPFQNIVDYAQISIKWPSTRIGTQLLDYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 462 Download |
| MASTNPGNKS TRFFSPHPHS HTQCTRTHQI AALALIVGTF FLTRLFDHSL SSCTSPYRNS 60 FSDPNQYIAP DDVVRFEGSG GYGTHLSLRI YVYDEDEIEG LKLLLYGREG KISADACVKG 120 QWGTQVKIHR LLLQSTFRTK KKEEADLFFV PSYVKCVRMM GGLSDKEINQ TYVKVLSQMP 180 YFRLSGGRNH VFVFPSGAGA HLFKSWATYL NRSIILTPEG DRTDKRDTTA FNTWKDIIIP 240 GNVDDGMTAH KSRLVDPLPL SRRKYLANYL GRAQGKAGRL QLIDLAKQYP DKLESPELKF 300 SGPEKLGRTE YFQHLRNAKF CLAPRGESSW TLRFYESFFV ECVPVLLSDQ AELPFQNIVD 360 YAQISIKWPS TRIGTQLLDY LESIPDKYIE DMIAKGRRVR CLWVYSPESE SCSAFRGILW 420 ELQKKVRKFH NSAETFWLHN GSIVNRDLVE FSKWKTPMPL P* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-40 | 88 | 384 | 312 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 12 | 461 | 10 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 5 | 461 | 3 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 5 | 461 | 3 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 5 | 461 | 3 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 2 | 461 | 3 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| GR165959 | 251 | 1 | 251 | 0 |
| CX668832 | 291 | 148 | 438 | 0 |
| GR005989 | 247 | 195 | 441 | 0 |
| EH692645 | 270 | 165 | 434 | 0 |
| FE707914 | 279 | 128 | 406 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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