Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a006113m |
Family | GT47 |
Protein Properties | Length: 457 Molecular Weight: 53399.3 Isoelectric Point: 10.1028 |
Chromosome | Chromosome/Scaffold: 30 Start: 1928056 End: 1930494 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 126 | 409 | 0 |
ESKFKVYIYREGEKPIFHNPYTRGIYASEGWFMKLMEKNKQFAVKDPKKAHMFYLPFSSVKLRNALNESGFRSQKDLENHLKKYVDIIATKYRFWNKRGG ADHFLVACHDWAPRSTRKIFENCTRALCNSNIAGGFKIGKDVSLPVTYIRSSENPLKDIEKNPSPNKTILAFFAGGMHGYVRPILLHYWQNKQPDMKIVG PMPRDIEGKAKYREFMKASKYCICAKGYEVHTPRVVESIYYECVPVIISDNYVPPLFEVFDWESFALFVLEKDIPNLREILLSV |
Full Sequence |
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Protein Sequence Length: 457 Download |
MKEINLNLVS IFEPEKPVLV LPKNLSLVHD KEPKIEGSDI SVTPISSALR KKGGKAMSIT 60 EMNSLLLVNS AEKKLKRPRL ASQRDRELQD AKYQILNAPI QRSISQVHAS LFRNYSMFVR 120 SYELMESKFK VYIYREGEKP IFHNPYTRGI YASEGWFMKL MEKNKQFAVK DPKKAHMFYL 180 PFSSVKLRNA LNESGFRSQK DLENHLKKYV DIIATKYRFW NKRGGADHFL VACHDWAPRS 240 TRKIFENCTR ALCNSNIAGG FKIGKDVSLP VTYIRSSENP LKDIEKNPSP NKTILAFFAG 300 GMHGYVRPIL LHYWQNKQPD MKIVGPMPRD IEGKAKYREF MKASKYCICA KGYEVHTPRV 360 VESIYYECVP VIISDNYVPP LFEVFDWESF ALFVLEKDIP NLREILLSVS EDRYAMMKRR 420 LKMVQRYFFW HKIPEKYDLF HMILHSVWYS RVFRVL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-58 | 125 | 409 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08970.1 | 0 | 3 | 455 | 98 | 556 | unnamed protein product [Arabidopsis thaliana] |
EMBL | CAN76867.1 | 0 | 38 | 455 | 251 | 710 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 38 | 455 | 251 | 662 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 38 | 455 | 249 | 660 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 38 | 455 | 251 | 666 | PREDICTED: hypothetical protein [Vitis vinifera] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES808098 | 337 | 92 | 428 | 0 |
EY168057 | 229 | 227 | 455 | 0 |
JG217834 | 294 | 167 | 455 | 0 |
JK987920 | 255 | 148 | 402 | 0 |
GT051299 | 334 | 116 | 444 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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