Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a006271m |
Family | GT47 |
Protein Properties | Length: 451 Molecular Weight: 51429.7 Isoelectric Point: 6.8232 |
Chromosome | Chromosome/Scaffold: 314 Start: 127891 End: 129441 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 37 | 387 | 0 |
CTNKWIHIRHLPPEFNLDLLKNCSEYPVFDNFCPYIPNHGLGHKTHNSSHSWYRTDPFMLELIFHRRILEYPCLTPDPVLADAVFLPYYAGIDSLKYLFG PEVNSSFLHGLDLYQYLTNSENTPSIWDRHHGHDHFLVMARPAWDFSQPVSNDPPVFGTSFLELPEFFNVTALTFEARAYPWQEQAVPYPTSFHPPNLAF LDSWMNRVRRSRRSTLMVFAGGGGISANPNVRRSIRLECENITNSVNANETGYSNLCEFVDCSNGVCEHDPIRFMKPMLQSSFCLQPPGDTPTRRSTFDG MLAGCVPVFFEELSARRQYTWHLPEEEYGEFSVFIAKEDVVGKGVKILDVL |
Full Sequence |
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Protein Sequence Length: 451 Download |
MPPPPLTPLF LLLVLITTTA VSAAAATTQD SDLESDCTNK WIHIRHLPPE FNLDLLKNCS 60 EYPVFDNFCP YIPNHGLGHK THNSSHSWYR TDPFMLELIF HRRILEYPCL TPDPVLADAV 120 FLPYYAGIDS LKYLFGPEVN SSFLHGLDLY QYLTNSENTP SIWDRHHGHD HFLVMARPAW 180 DFSQPVSNDP PVFGTSFLEL PEFFNVTALT FEARAYPWQE QAVPYPTSFH PPNLAFLDSW 240 MNRVRRSRRS TLMVFAGGGG ISANPNVRRS IRLECENITN SVNANETGYS NLCEFVDCSN 300 GVCEHDPIRF MKPMLQSSFC LQPPGDTPTR RSTFDGMLAG CVPVFFEELS ARRQYTWHLP 360 EEEYGEFSVF IAKEDVVGKG VKILDVLMNI PRAEIRRKRE KVMEMLPRIM YRKHGSSLGL 420 RSKKDAFDIA IEGTLQRIKS RTQQFAALRK * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-51 | 81 | 377 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 21 | 442 | 21 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 8 | 446 | 5 | 442 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 26 | 441 | 18 | 428 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 7 | 443 | 5 | 433 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 10 | 443 | 13 | 450 | catalytic, putative [Ricinus communis] |